Preparation of a pH-sensitive polystyrene fluorescent microsphere based on a cyanine dye

被引：8

作者：

Yu, Liang ^{[1
]}

Wang, Qiuling ^{[2
]}

Li, Tingting ^{[1
]}

Chen, Ligong ^{[1
]}

机构：

[1] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China

[2] Tianjin Univ, Sch Pharmaceut & Biotechnol, Tianjin 300072, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2012年 / 11期

关键词：

near-infrared label; pH-sensitivity; fluorescent microsphere; cyanine; MONODISPERSE;

D O I：

10.3184/174751912X13466874476971

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel pH-sensitive near-IR (NIR) fluorescent dye was synthesised and utilised in the preparation of fluorescent polystyrene microspheres. Their photochemical properties, as well as the pH-dependent optical properties were investigated and showed high sensitivity to changes of pH in the range of 3.3-8.1. The fluorescence became stronger with the increase in pH. Importantly, the microspheres were able to work in aqueous media, which is highly valuable for use in biological applications.

引用

页码：632 / 634

页数：3

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