Preparation of a pH-sensitive polystyrene fluorescent microsphere based on a cyanine dye

被引:8
|
作者
Yu, Liang [1 ]
Wang, Qiuling [2 ]
Li, Tingting [1 ]
Chen, Ligong [1 ]
机构
[1] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China
[2] Tianjin Univ, Sch Pharmaceut & Biotechnol, Tianjin 300072, Peoples R China
关键词
near-infrared label; pH-sensitivity; fluorescent microsphere; cyanine; MONODISPERSE;
D O I
10.3184/174751912X13466874476971
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel pH-sensitive near-IR (NIR) fluorescent dye was synthesised and utilised in the preparation of fluorescent polystyrene microspheres. Their photochemical properties, as well as the pH-dependent optical properties were investigated and showed high sensitivity to changes of pH in the range of 3.3-8.1. The fluorescence became stronger with the increase in pH. Importantly, the microspheres were able to work in aqueous media, which is highly valuable for use in biological applications.
引用
收藏
页码:632 / 634
页数:3
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