Heteropoly acids as solid green Bronsted acids for a one-pot synthesis of β-acetamido ketones by Dakin-West reaction

被引:78
|
作者
Rafiee, E [1 ]
Tork, F
Joshaghani, M
机构
[1] Razi Univ, Fac Sci, Dept Chem, Kermanshah 67149, Iran
[2] Kermanshah Oil Refining Co, Kermanshah, Iran
关键词
beta-acetamido ketones; heteropoly acid; Dakin-West reaction; multi component reactions (MCRs);
D O I
10.1016/j.bmcl.2005.11.080
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
An efficient improved procedure for the synthesis of beta-acetamido ketones has been developed by a heteropoly acid (HPA) catalyzed three-component coupling protocol. The present methodology offers several advantages such as excellent yields, simple procedure, short reaction times, and mild conditions. (C) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1221 / 1226
页数:6
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