Noise filtration in fluorescence-enhanced optical tomography: breast phantom studies

被引：1

作者：

Zhu, Banghe ^{[1
]}

Sevick-Muraca, Eva M. ^{[2
]}

Eppstein, Margaret J. ^{[3
]}

Godavarty, Anuradha ^{[1
]}

机构：

[1] Florida Int Univ, Dept Biomed Engn, Miami, FL 33199 USA

[2] Baylor Coll Med, Dept Radiol, Houston, TX 77030 USA

[3] Univ Vermont, Dept Comp Sci, Burlington, VT USA

来源：

INVERSE PROBLEMS IN SCIENCE AND ENGINEERING | 2009年 / 17卷 / 01期

关键词：

noise pre-filtration; fluorescence-enhanced optical tomography; optical imaging technique; IN-VIVO;

D O I：

10.1080/17415970802083482

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Noisy measurements may impact the quality of image reconstructions in fluorescence-enhanced optical tomography studies. In this contribution, different noise pre-filtration techniques were developed using fluorescence measurements of homogeneous breast phantoms. The noise pre-filtration techniques were determined based on correlation studies among various measurement parameters. We demonstrated that noise pre-filtration techniques can improve the target localization in image reconstructions when the target is deeply located (2 cm) in imperfect uptake case (i.e. target: background fluorescence absoroption contrast ratio of 100 : 1). Moreover, filtration of measurement noise using different criteria can possibly differentiate the target from artifacts, potentially minimizing the false-positive cases in a clinical environment.

引用

页码：97 / 104

页数：8

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