Hemoglobin contrast in magnetomotive optical Doppler tomography

被引:16
|
作者
Kim, J
Oh, J
Milner, TE
Nelson, JS
机构
[1] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92612 USA
[2] Univ Texas, Dept Biomed Engn, Austin, TX 78712 USA
关键词
D O I
10.1364/OL.31.000778
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We introduce a novel contrast mechanism for imaging blood flow by use of magnetornotive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect erythrocytes moving according to the field gradient. Hemoglobin contrast was demonstrated in a capillary tube filled with moving blood by imaging the Doppler frequency shift, which was observed independently of blood flow rate and direction. Results suggest that MM-ODT may be a promising technique with which to image blood flow. (c) 2006 Optical Society of America.
引用
收藏
页码:778 / 780
页数:3
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