FPGA-Based Lock-In Amplifier for Measuring the Electrical Properties of Individual Cells

被引:0
|
作者
Divakar, Dipin [1 ]
Mahesh, Karthik [1 ]
Varma, Manoj M. [1 ]
Sen, Prosenjit [1 ]
机构
[1] Indian Inst Sci, Ctr Nano Sci & Engn CeNSE, Bangalore, Karnataka, India
关键词
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We report the design and validation of a low-cost and portable FPGA-based lock-in amplifier (LIA) for measuring the dielectric properties of cells through electrical impedance spectroscopy (EIS). The proposed design uses the phase sensitive measurement principle which detects the signal at a particular reference frequency and rejects the rest. By closely integrating the LIA with a custom-built instrumentation amplifier and a microfluidic device, we demonstrate the excellent ability of the system to suppress noise and detect impedance changes due to flowing red blood cells (RBCs).
引用
收藏
页码:413 / 416
页数:4
相关论文
共 50 条
  • [21] Lock-in amplifier based peak force infrared microscopy
    Dorsa, Andrea
    Xie, Qing
    Wagner, Martin
    Xu, Xiaoji G.
    ANALYST, 2023, 148 (02) : 227 - 232
  • [22] Digital lock-in amplifier based on DSP and sampling ADC
    Hu, Shaomin
    Zhang, Guangfa
    Shu Ju Cai Ji Yu Chu Li/Journal of Data Acquisition & Processing, 2000, 15 (02): : 222 - 225
  • [23] Implementation of Digital Lock-in Amplifier Based on System Generator
    Wang, Qingfeng
    Zheng, Hong
    Jiang, Meng
    2016 IEEE INTERNATIONAL CONFERENCE ON SIGNAL AND IMAGE PROCESSING (ICSIP), 2016, : 636 - 640
  • [24] LOCK-IN AMPLIFIER BASED ON A SYNCHRONOUSLY CLOCKED TRANSVERSAL FILTER
    CODDING, EG
    ANALYTICAL CHEMISTRY, 1979, 51 (12) : 1981 - 1986
  • [25] INSTRUMENTATION FOR AC VOLTAMMETRY BASED ON A DIGITAL LOCK-IN AMPLIFIER
    CURRAN, DJ
    KINGSLEY, ED
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1982, 183 (MAR): : 14 - ANYL
  • [26] FPGA-based Real-time Harmonic Impedance Measurement of Series Resonant Loads by Using Lock-in Algorithm
    Jimenez, O.
    Barragan, L. A.
    Urriza, I.
    Lucia, O.
    Navarro, D.
    Artigas, J. I.
    IECON 2011: 37TH ANNUAL CONFERENCE ON IEEE INDUSTRIAL ELECTRONICS SOCIETY, 2011,
  • [27] A miniaturized lock-in amplifier design suitable for impedance measurements in cells
    Moe, AE
    Marx, SR
    Bhinderwala, I
    Wilson, DM
    PROCEEDINGS OF THE IEEE SENSORS 2004, VOLS 1-3, 2004, : 215 - 218
  • [28] Properties of Fiber Optic DNA Sensor Based on Fluorescence Quenching Using Lock-in Amplifier
    Fang, Hua
    Wang, Yourong
    Ding, Liyun
    MECHATRONICS, ROBOTICS AND AUTOMATION, PTS 1-3, 2013, 373-375 : 302 - +
  • [29] A Mechatronic Lock-In Amplifier: Integrating Demodulation in Sensor Electronics for Measuring Mechanical Oscillations
    Poik, Mathias
    Kohl, Dominik
    Mayr, Mario
    Kerschner, Christoph
    Schitter, Georg
    IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2021, 70
  • [30] Software simulation of a lock-in amplifier with application to the evaluation of uncertainties in real measuring systems
    Clarkson, P.
    Esward, T. J.
    Harris, P. M.
    Smith, A. A.
    Smith, I. M.
    MEASUREMENT SCIENCE AND TECHNOLOGY, 2010, 21 (04)