Rapid Natural-Abundance 2D 13C-13C Correlation Spectroscopy Using Dynamic Nuclear Polarization Enhanced Solid-State NMR and Matrix-Free Sample Preparation

被引：151
|
作者：
Takahashi, Hiroki [1 ,2 ]
Lee, Daniel [1 ,2 ]
Dubois, Lionel [1 ,2 ]
Bardet, Michel [1 ,2 ]
Hediger, Sabine [1 ,2 ]
De Paepe, Gael [1 ,2 ]
机构：
[1] UMR E3 CEA UJF, Lab Chim Inorgan & Biol, F-38054 Grenoble, France
[2] Inst Nanosci & Cryogenie CEA DSM, CNRS, F-38054 Grenoble, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 47期
关键词：
2D correlation; analytical methods; dynamic nuclear polarization; natural abundance; NMR spectroscopy; RESONANCE; MEMBRANES; PROTEINS;
D O I：
10.1002/anie.201206102
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Ultra-fast: Substantial solid-state NMR sensitivity can be achieved using dynamic nuclear polarization and matrix-free sample preparation (that is, absence of solvent and cryoprotectant). This method avoids line-broadening, maximizes sample filling factor, and allows natural-abundance 2D 13C-13C dipolar correlation experiments to be carried out in tens of minutes. MW=microwaves. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：11766 / 11769
页数：4
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