Methylenecyclopropane analogues of nucleosides:: Synthesis, absolute configuration, and enantioselectivity of antiviral effect of (R)-(-)- and (S)-(+)-synadenol

被引：3
|
作者：
Qiu, YL
Hempel, A
Camerman, N
Camerman, A
Geiser, F
Ptak, RG
Breitenbach, JM
Kira, T
Li, L
Gullen, E
Cheng, YC
Drach, JC
Zemlicka, J [1 ]
机构：
[1] Wayne State Univ, Sch Med, Barbara Ann Karmanos Canc Inst, Detroit, MI 48201 USA
[2] Univ Toronto, Dept Biochem, Toronto, ON M5S 1A8, Canada
[3] Ardono Res, Seattle, WA 98105 USA
[4] Chiral Technol Inc, Exton, PA 19341 USA
[5] Yale Univ, Sch Med, Dept Pharmacol, New Haven, CT 06510 USA
[6] Univ Michigan, Sch Dent, Dept Biol & Mat Sci, Ann Arbor, MI 48019 USA
来源：
NUCLEOSIDES & NUCLEOTIDES | 1999年 / 18卷 / 4-5期
关键词：
D O I：
10.1080/15257779908041507
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Synthesis, absolute configuration and antiviral activity of enantiomeric antiviral agents (R)-(-)- and (S)-(+)-synadenol (2 and 3a) are described.
引用
收藏
页码：597 / 598
页数：2
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