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- [21] Discovery of WS-157 as a highly potent,selective and orally active EGFR inhibitorActa Pharmaceutica Sinica B, 2019, 9 (06) : 1193 - 1203Pengxing HeShenghui NiuShuai WangXiaojing ShiSiqi FengLinna DuXuyang ZhangZhilu MaBin YuHongmin Liu
- [22] Potent and highly selective cyclooxygenase-2 (COX-2) inhibitor from a novel, pyridyl metharyl series.ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 228 : U951 - U951Khanapure, SPAugustyniak, MEEarl, RAGarvey, DSLetts, LGMartino, AMMurty, MGSchwalb, DSShumway, MJTrocha, AMYoung, DVZemtseva, ISJanero, DR
- [23] Discovery of a series of potent, orally active α,α-disubstituted piperidine NK1 antagonistsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (21) : 6313 - 6315Xiao, DongWang, ChengPalani, AnandanTsui, Hon-ChungReichard, GregoryPaliwal, SunilShih, Neng-YangAslanian, RobertDuffy, RuthLachowicz, JeanVarty, GeoffreyMorgan, CynthiaLiu, FeiNomeir, Amin
- [24] Effect of an orally active COX-2 inhibitor on the development of gallbladder carcinoma in BK5.erbB2 mice.CANCER RESEARCH, 2006, 66 (08)Kiguchi, KaoruKawamoto, ToruRuffino, LynnsieHanai, MasaharuFujiwara, KosakuDigiovanni, John
- [25] BLX-1031, an orally active, novel dual inhibitor of COX-2 and TNF-α for the treatment of inflammatory disordersIMMUNOLOGY 2004: AUTOIMMUNITY, GENETIC AND DEGENERATIVE DISORDERS, MALIGNANCIES, AND TRANSPLANTATION, 2004, : 197 - 201Pandey, BNag, ANeogi, PAgarwal, SKSriram, SNag, BDey, D
- [26] DISCOVERY OF A NOVEL AND POTENT CHOLESTEROL ABSORPTION INHIBITOR AS PROMISING ORALLY ACTIVE LIPID LOWERING DRUGATHEROSCLEROSIS SUPPLEMENTS, 2010, 11 (02) : 79 - 79Kanou, M.Nishiwaki, Y.Nakano, A.Yamanaka, Y.
- [27] Discovery of a Novel, Potent, Orally Active, and Safe Inhibitor Targeting Human Mitochondrial RNA PolymeraseJOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (07) : 5118 - 5153Li, XinnanZe, XiaotongZhou, ShengnanHu, ZhaoxinHe, ChenJia, YilinLiu, LihuaWang, TaoLi, JundaXu, ShengtaoYang, Dong-HuaChen, Zhe-ShengYao, HequanXu, JinyiYao, Hong
- [28] Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2022, 65 (16) : 10882 - 10897Iijima, DaisukeSugama, HiroshiTakahashi, YoichiHirai, MikiTogashi, YukoXie, JianshuShen, JingkangKe, YingAkatsuka, HidenoriKawaguchi, TakayukiTakedomi, KeiKashima, AkikoNishio, MasashiInui, YosukeYoneda, HikaruXia, GuangxinIijima, Toru
- [29] Discovery of a Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitor for the Potential Treatment of SchizophreniaJOURNAL OF MEDICINAL CHEMISTRY, 2014, 57 (10) : 4196 - 4212Manuel Bartolome-Nebreda, JoseDelgado, FranciscaLuz Martin-Martin, MariaMartinez-Viturro, Carlos M.Pastor, JoaquinMin Tong, HanIturrino, LauraMacdonald, Gregor J.Sanderson, WendyMegens, AntonLanglois, XavierSomers, MarijkeVanhoof, GreetConde-Ceide, Susana
- [30] Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 630 (1-3) : 34 - 41Shimamura, KenNagumo, AkiraMiyamoto, YasuhisaKitazawa, HidefumiKanesaka, MakiYoshimoto, RyoAragane, KatsumiMorita, NaomiOhe, TomoyukiTakahashi, ToshiyukiNagase, TsuyoshiSato, NagaakiTokita, Shigeru