共 50 条
- [1] DISCOVERY OF A NOVEL AND POTENT CHOLESTEROL ABSORPTION INHIBITOR (CAI) AS PROMISING ORALLY ACTIVE LIPID LOWERING DRUGATHEROSCLEROSIS SUPPLEMENTS, 2009, 10 (02)Kanou, M.Nisiwaki, Y.Nakano, A.Sugimoto, Y.Yamanaka, Y.Kondo, S.
- [2] Discovery of TAK-272: A Novel, Potent, and Orally Active Renin InhibitorACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (10): : 933 - 938Imaeda, YasuhiroTokuhara, HidekazuFukase, YoshiyukiKanagawa, RayKajimoto, YumikoKusumoto, KeijiKondo, MitsuyoSnell, GyorgyBehnke, Craig A.Kuroita, Takanobu
- [3] Discovery and development of anacetrapib, a potent and orally active CETP inhibitorABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243Ali, Amjad
- [4] Discovery of a Novel, Potent, Orally Active, and Safe Inhibitor Targeting Human Mitochondrial RNA PolymeraseJOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (07) : 5118 - 5153Li, XinnanZe, XiaotongZhou, ShengnanHu, ZhaoxinHe, ChenJia, YilinLiu, LihuaWang, TaoLi, JundaXu, ShengtaoYang, Dong-HuaChen, Zhe-ShengYao, HequanXu, JinyiYao, Hong
- [5] Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2022, 65 (16) : 10882 - 10897Iijima, DaisukeSugama, HiroshiTakahashi, YoichiHirai, MikiTogashi, YukoXie, JianshuShen, JingkangKe, YingAkatsuka, HidenoriKawaguchi, TakayukiTakedomi, KeiKashima, AkikoNishio, MasashiInui, YosukeYoneda, HikaruXia, GuangxinIijima, Toru
- [6] Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 630 (1-3) : 34 - 41Shimamura, KenNagumo, AkiraMiyamoto, YasuhisaKitazawa, HidefumiKanesaka, MakiYoshimoto, RyoAragane, KatsumiMorita, NaomiOhe, TomoyukiTakahashi, ToshiyukiNagase, TsuyoshiSato, NagaakiTokita, Shigeru
- [7] Discovery of a potent, selective, and orally active proteasome inhibitor for the treatment of cancerJOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (04) : 1068 - 1072Dorsey, Bruce D.Iqbal, MohamedChatterjee, SankarMenta, ErnestoBernardini, RaffaellaBernareggi, AlbertoCassara, Paolo G.D'Arasmo, GermanoFerretti, EdmondoDe Munari, SergioOliva, AmbrogioPezzoni, GabriellaAllievi, CeciliaStrepponi, IvanRuggeri, BruceAtor, Mark A.Williams, MichaelMallamoT, John P.
- [8] Discovery of DS79182026: A potent orally active hepcidin production inhibitorBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (16) : 3716 - 3722Fukuda, TakeshiGoto, RikiKiho, ToshihiroUeda, KenjiroMuramatsu, SumieHashimoto, MasamiAid, AnriWatanabe, KengoTanaka, Naoki
- [9] Discovery of DS-5272 as a promising candidate: A potent and orally active p53-MDM2 interaction inhibitorBIOORGANIC & MEDICINAL CHEMISTRY, 2015, 23 (10) : 2360 - 2367Miyazaki, MasakiUoto, KouichiSugimoto, YuuichiNaito, HiroyukiYoshida, KeisukeOkayama, TooruKawato, HarukoMiyazaki, MasayaKitagawa, MayumiSeki, TakahikoFukutake, SetsukoAonuma, MasashiSoga, Tsunehiko
- [10] Discovery of WS-157 as a highly potent, selective and orally active EGFR inhibitorACTA PHARMACEUTICA SINICA B, 2019, 9 (06) : 1193 - 1203He, PengxingNiu, ShenghuiWang, ShuaiShi, XiaojingFeng, SiqiDu, LinnaZhang, XuyangMa, ZhiluYu, BinLiu, Hongmin