Novel Antihypertensive Therapies: Renal Sympathetic Nerve Ablation and Carotid Baroreceptor Stimulation

被引：7
|
作者：
Grassi, Guido [1 ,2 ,3 ]
Seravalle, Gino [2 ]
Brambilla, Gianmaria [2 ]
Bombelli, Michele [2 ]
Dell'Oro, Raffaella [2 ]
Gronda, Edoardo [3 ]
Mancia, Giuseppe [2 ]
机构：
[1] Univ Milano Bicocca, San Gerardo Hosp, Med Clin, I-20052 Monza, MI, Italy
[2] Univ Milano Bicocca, Dept Clin Med & Prevent, Med Clin, I-20052 Monza, MI, Italy
[3] Ist Ric & Cura Carattere Sci Multimed, Milan, Italy
来源：
CURRENT HYPERTENSION REPORTS | 2012年 / 14卷 / 06期
关键词：
Hypertension; Blood pressure; Resistant hypertension; Interventions; Renal denervation; Carotid baroreceptor stimulation; End-organ damage; Insulin; Side effects; BAROREFLEX ACTIVATION THERAPY; RESISTANT HYPERTENSION; BLOOD-PRESSURE; DOUBLE-BLIND; DENERVATION; SPIRONOLACTONE;
D O I：
10.1007/s11906-012-0312-5
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
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页码：567 / 572
页数：6
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