⁢In Vivo⁢ Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

被引：26

作者：

Ke, Bowen ^{[2
]}

Ma, Lin ^{[1
]}

Kang, Ting ^{[2
]}

He, Wei ^{[2
]}

Gou, Xueyan ^{[2
]}

Gong, Deying ^{[2
]}

Du, Lupei ^{[1
]}

Li, Minyong ^{[1
]}

机构：

[1] Shandong Univ, Dept Med Chem, Key Lab Chem Biol MOE, Sch Pharm, Jinan 250012, Shandong, Peoples R China

[2] Sichuan Univ, West China Hosp, Translat Neurosci Ctr, Dept Anaesthesiol & Crit Care Med,West China Brai, Chengdu 610041, Sichuan, Peoples R China

来源：

ANALYTICAL CHEMISTRY | 2018年 / 90卷 / 08期

基金：

中国国家自然科学基金;

关键词：

INTRAMOLECULAR PROTON-TRANSFER; IN-VIVO; MURINE MODEL; METAL-IONS; PROBE; COPPER; CO2+; VITAMIN-B-12; SPECTROMETRY; RECOGNITION;

D O I：

10.1021/acs.analchem.8b00391

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

As a trace element nutrient, cobalt is critical for both prokaryotes and eukaryotes. In the current study, a turn-on Cobalt Bioluminescent Probe 1 (CBP-1) for the detection of cobalt has been successfully developed based on oxidative C-O bond cleavage. This probe exhibited high selectivity and sensitivity toward cobalt over other analytes. By using CBP-1, the successful in vivo imaging of cobalt accumulation was carried out in a mouse model. Such an ability to determine cobalt in living animals provides a powerful technology for studying the system distribution, toxic potency, and biological effect of Co2+.

引用

页码：4946 / 4950

页数：5

共 50 条

[41] In vivo imaging of autophagy in a mouse stroke model
Tian, FengFeng
Deguchi, Kentaro
Yamashita, Toru
Ohta, Yasuyuki
Morimoto, Nobutoshi
Shang, Jingwei
Zhang, Xuemei
Liu, Ning
Ikeda, Yoshio
Matsuura, Tohru
Abe, Koji
AUTOPHAGY, 2010, 6 (08) : 1107 - 1114
[42] A transgenic mouse model for the in vivo bioluminescence imaging of the expression of the lysophosphatidic acid receptor 3: relevance for inflammation and uterine physiology research
Chenqi Zhao
Anne Sardella
Lynn Davis
Patrice E. Poubelle
Sylvain G. Bourgoin
Maria J. Fernandes
Transgenic Research, 2015, 24 : 625 - 634
[43] A transgenic mouse model for the in vivo bioluminescence imaging of the expression of the lysophosphatidic acid receptor 3: relevance for inflammation and uterine physiology research
Zhao, Chenqi
Sardella, Anne
Davis, Lynn
Poubelle, Patrice E.
Bourgoin, Sylvain G.
Fernandes, Maria J.
TRANSGENIC RESEARCH, 2015, 24 (04) : 625 - 634
[44] An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging
Vick, Binje
Rothenberg, Maja
Sandhoefer, Nadine
Carlet, Michela
Finkenzeller, Cornelia
Krupka, Christina
Grunert, Michaela
Trumpp, Andreas
Corbacioglu, Selim
Ebinger, Martin
Andre, Maya C.
Hiddemann, Wolfgang
Schneider, Stephanie
Subklewe, Marion
Metzeler, Klaus H.
Spiekermann, Karsten
Jeremias, Irmela
PLOS ONE, 2015, 10 (03):
[45] Bioluminescence in vivo Imaging using a Cypridina Luciferase
Ohmiya, Yoshihiro
Wu, Chun
LUMINESCENCE, 2012, 27 (02) : 150 - 150
[46] Advances in vivo bioluminescence imaging of gene expression
Contag, CH
Bachmann, MH
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2002, 4 : 235 - 260
[47] In vivo bioluminescence imaging for integrated studies of infection
Doyle, TC
Burns, SM
Contag, CH
CELLULAR MICROBIOLOGY, 2004, 6 (04) : 303 - 317
[48] In vivo cell tracking by using bioluminescence imaging
Klementieva, N.
Shirmanova, M.
Serebrovskaya, E.
Fradkov, A.
Zagaynova, E.
FEBS JOURNAL, 2013, 280 : 601 - 601
[49] Quantitative Bioluminescence Imaging of Transgene Expression In Vivo
Rettig, Garrett R.
McAnuff, Marie
Liu, Dijie
Kim, Ji-Seon
Rice, Kevin G.
MOLECULAR THERAPY, 2006, 13 : S154 - S154
[50] Bioluminescence imaging correlates with tumor progression in an orthotopic mouse model of lung cancer
Madero-Visbal, Rafael A.
Colon, Jimmie F.
Hernandez, Ingrid C.
Limaye, Arati
Smith, Joshua
Lee, Christopher M.
Arlen, Philip A.
Herrera, Luis
Baker, Cheryl H.
SURGICAL ONCOLOGY-OXFORD, 2012, 21 (01): : 23 - 29

← 1 2 3 4 5 →