⁢In Vivo⁢ Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

被引：26

作者：

Ke, Bowen ^{[2
]}

Ma, Lin ^{[1
]}

Kang, Ting ^{[2
]}

He, Wei ^{[2
]}

Gou, Xueyan ^{[2
]}

Gong, Deying ^{[2
]}

Du, Lupei ^{[1
]}

Li, Minyong ^{[1
]}

机构：

[1] Shandong Univ, Dept Med Chem, Key Lab Chem Biol MOE, Sch Pharm, Jinan 250012, Shandong, Peoples R China

[2] Sichuan Univ, West China Hosp, Translat Neurosci Ctr, Dept Anaesthesiol & Crit Care Med,West China Brai, Chengdu 610041, Sichuan, Peoples R China

来源：

ANALYTICAL CHEMISTRY | 2018年 / 90卷 / 08期

基金：

中国国家自然科学基金;

关键词：

INTRAMOLECULAR PROTON-TRANSFER; IN-VIVO; MURINE MODEL; METAL-IONS; PROBE; COPPER; CO2+; VITAMIN-B-12; SPECTROMETRY; RECOGNITION;

D O I：

10.1021/acs.analchem.8b00391

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

As a trace element nutrient, cobalt is critical for both prokaryotes and eukaryotes. In the current study, a turn-on Cobalt Bioluminescent Probe 1 (CBP-1) for the detection of cobalt has been successfully developed based on oxidative C-O bond cleavage. This probe exhibited high selectivity and sensitivity toward cobalt over other analytes. By using CBP-1, the successful in vivo imaging of cobalt accumulation was carried out in a mouse model. Such an ability to determine cobalt in living animals provides a powerful technology for studying the system distribution, toxic potency, and biological effect of Co2+.

引用

页码：4946 / 4950

页数：5

共 50 条

[21] Bioluminescence imaging for in vivo monitoring of local recurrence mesothelioma model
Shi, Yandong
Hollenstein, Andreas
Felley-Bosco, Emanuela
Fraefel, Cornel
Ackermann, Matthias
Soltermann, Alex
Weder, Walter
Stahel, Rolf
Pruschy, Martin
Opitz, Isabelle
LUNG CANCER, 2011, 71 (03) : 370 - 371
[22] Real-Time Bioluminescence Imaging of Nitroreductase in Mouse Model
Feng, Ping
Zhang, Huateng
Deng, Quankun
Liu, Wei
Yang, Linghui
Li, Guobo
Chen, Guo
Du, Lupei
Ke, Bowen
Li, Minyong
ANALYTICAL CHEMISTRY, 2016, 88 (11) : 5610 - 5614
[23] In vivo mouse 99mTc SPECT scans with bioluminescence imaging validation
Liang, Zhi-Xin
Qiang, Yong-Gang
Liao, Yong-Hua
Zhu, Xu-Sheng
Huang, Zheng
Zhang, Xiu-Ping
Wang, Luping
JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY, 2013, 21 (01) : 85 - 91
[24] Visualization of mercury(II) accumulation in vivo using bioluminescence imaging with a highly selective probe
Ke, Bowen
Chen, Hui
Ma, Lin
Zingales, Sarah
Gong, Deying
Hu, Die
Du, Lupei
Li, Minyong
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 16 (14) : 2388 - 2392
[25] A New Gastric-Emptying Mouse Model Based on In Vivo Non-Invasive Bioluminescence Functional Imaging
Roda, Aldo
Mezzanotte, Laura
Aldini, Rita
Michelini, Elisa
Cevenini, Luca
Coppa, Andrea
GASTROENTEROLOGY, 2010, 138 (05) : S65 - S65
[26] In vivo mouse studies with bioluminescence tomography
Wang, Ge
Cong, Wenxiang
Durairaj, Kumar
Qian, Xin
Shen, Haiou
Sinn, Patrick
Hoffman, Eric
McLennan, Geoffrey
Henry, Michael
OPTICS EXPRESS, 2006, 14 (17): : 7801 - 7809
[27] An experimental brainstem tumor model using in vivo bioluminescence imaging in rat
Kondo, Akihide
Goldman, Stewart
Vanin, Elio F.
Sredni, Simone T.
Rajaram, Veena
Soares, Marcelo B.
Tomita, Tadanori
CHILDS NERVOUS SYSTEM, 2009, 25 (05) : 527 - 533
[28] An experimental brainstem tumor model using in vivo bioluminescence imaging in rat
Akihide Kondo
Stewart Goldman
Elio F. Vanin
Simone T. Sredni
Veena Rajaram
Marcelo B. Soares
Tadanori Tomita
Child's Nervous System, 2009, 25 : 527 - 533
[29] Bioluminescence imaging of Arc expression in vivo
Izumi, Hironori
Ishimoto, Tetsuya
Mori, Hisashi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115 : 228P - 228P
[30] In Vivo Cell Tracking with Bioluminescence Imaging
Kim J.E.
Kalimuthu S.
Ahn B.-C.
Nuclear Medicine and Molecular Imaging, 2015, 49 (1) : 3 - 10

← 1 2 3 4 5 →