Novel imidazolopyrimidines as dual PI3-kinase/mTor inhibitors

被引：0

作者：

Dehnhardt, Christoph ^{[1
]}

Venkatesan, Aranapakam ^{[1
]}

Chen, Zecheng ^{[1
]}

Delos Santos, Efren ^{[1
]}

Santos, Oswaldo ^{[1
]}

Bursavich, Matthew ^{[1
]}

Brooijmans, Natasja ^{[1
]}

Mallon, Robert ^{[1
]}

Hollander, Irwin ^{[1
]}

Feldberg, Larry ^{[1
]}

Lucas, Judy ^{[1
]}

Yu, Ker ^{[1
]}

Ayral-Kaloustian, Semiramis ^{[1
]}

Gibbons, Jay ^{[1
]}

Abraham, Robert ^{[1
]}

Mansour, Tarek ^{[1
]}

机构：

[1] Wyeth Res, Pearl River, NY USA

来源：

CANCER RESEARCH | 2009年 / 69卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

2017

引用

页数：1

共 50 条

[41] PI3-kinase superfamily: Structures and functions
Kimura, K
Fukui, Y
SEIKAGAKU, 1996, 68 (05): : 362 - 367
[42] PI3-kinase, the key for bugs to get in?
Lauvau, Gregoire
JOURNAL OF EXPERIMENTAL MEDICINE, 2015, 212 (02): : 127 - 127
[43] Activating PI3-Kinase to Dampen Inflammation
Kok, Bernard P.
Saez, Enrique
CHEMISTRY & BIOLOGY, 2014, 21 (08): : 917 - 918
[44] Selective sensitisation of tumour cells to the induction of apoptosis with inhibitors of PI3-kinase and PKC
O'Gorman, D
McGahon, A
Cotter, TG
BRITISH JOURNAL OF CANCER, 1998, 78 : 35 - 35
[45] Discovery and Toxicological Profiling of Aminopyridines as Orally Bioavailable Selective Inhibitors of PI3-Kinase γ
Bellenie, Benjamin R.
Hall, Edward
Bruce, Ian
Spendiff, Matthew
Culshaw, Andrew
McDonald, Sarah
Ambarkhane, Ameet
Chinn, Colin
Thomas, Matthew
Rosner, Elisabeth
Bracher, Marguerite
Nicklin, Paul
Marshall, Stephen
Coote, Julie
Cullen, Eva
Tessier, Clemence
Wuersch, Kuno
Lal, Ajay
Wallis, Gillian
Hollingworth, Gregory J.
Neef, James
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (16) : 12304 - 12321
[46] The role of PDGF receptor inhibitors and PI3-kinase signaling in the pathogenesis of corneal neovascularization
Dell, Susanne
Peters, Swaantje
Muether, Philipp
Kociok, Norbert
Joussen, Antonia M.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2006, 47 (05) : 1928 - 1937
[47] PTEN and the PI3-Kinase Pathway in Cancer
Chalhoub, Nader
Baker, Suzanne J.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2009, 4 : 127 - 150
[48] Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway
Bruce, Ian
Akhlaq, Mohammed
Bloomfield, Graham C.
Budd, Emma
Cox, Brian
Cuenoud, Bernard
Finan, Peter
Gedeck, Peter
Hatto, Julia
Hayler, Judy F.
Head, Denise
Keller, Thomas
Kirman, Louise
Leblanc, Catherine
Le Grand, Darren
McCarthy, Clive
O'Connor, Desmond
Owen, Charles
Oza, Mrinalini S.
Pilgrim, Gaynor
Press, Nicola E.
Sviridenko, Lilya
Whitehead, Lewis
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (17) : 5445 - 5450
[49] A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia
Fabian Lang
Lydia Wunderle
Susanne Badura
Eberhard Schleyer
Monika Brüggemann
Hubert Serve
Susanne Schnittger
Nicola Gökbuget
Heike Pfeifer
Sebastian Wagner
Kevin Ashelford
Gesine Bug
Oliver G. Ottmann
BMC Pharmacology and Toxicology, 21
[50] A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia
Lang, Fabian
Wunderle, Lydia
Badura, Susanne
Schleyer, Eberhard
Brueggemann, Monika
Serve, Hubert
Schnittger, Susanne
Goekbuget, Nicola
Pfeifer, Heike
Wagner, Sebastian
Ashelford, Kevin
Bug, Gesine
Ottmann, Oliver G.
BMC PHARMACOLOGY & TOXICOLOGY, 2020, 21 (01):

← 1 2 3 4 5 →