Loss of the type Ill TGF-β receptor during cancer progression generates an immunotolerant tumor microenvironment: Translational implications for TGF-β inhibition and immunotherapy biomarker development

被引：0

作者：

Hanks, Brent A. ^{[1
]}

Holtzhausen, Alisha ^{[1
]}

Gimpel, Petra ^{[2
]}

Campbell, Olivia ^{[1
]}

Jamieson, Rebekah ^{[1
]}

Ling, Leona E. ^{[3
]}

Morse, Michael A. ^{[1
]}

Lyerly, H. K. ^{[1
]}

Blobe, Gerard ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Durham, NC USA

[2] Free Univ Berlin, Berlin, Germany

[3] Biogen Idec Inc, Cambridge, MA USA

来源：

CANCER RESEARCH | 2012年 / 72卷

关键词：

D O I：

10.1158/1538-7445.AM2012-3548

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

3548

引用

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页数：1

共 45 条

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[42] Effect of conditional knockout of the type II TGF-β receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis
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[43] Loss Of The Transforming Growth Factor-Beta (TGF-) Receptor In The Mutated K-RAS Orthotopic Model Of Murine Lung Cancer Parallels The Progression Of Human Bronchioloalveolar Cell Carcinoma To Invasive Adenocarcinoma
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[44] Sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: Implication for the loss of TGF-β type II receptor expression
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Yong Seok Kim
Byung-Kiu Park
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Oncogene, 2001, 20 : 1235 - 1245
[45] A sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: Implication for the loss of TGF-[beta] type II receptor expression
Park, SH
FASEB JOURNAL, 2001, 15 (05): : A881 - A881

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