Loss of the type Ill TGF-β receptor during cancer progression generates an immunotolerant tumor microenvironment: Translational implications for TGF-β inhibition and immunotherapy biomarker development

被引：0

作者：

Hanks, Brent A. ^{[1
]}

Holtzhausen, Alisha ^{[1
]}

Gimpel, Petra ^{[2
]}

Campbell, Olivia ^{[1
]}

Jamieson, Rebekah ^{[1
]}

Ling, Leona E. ^{[3
]}

Morse, Michael A. ^{[1
]}

Lyerly, H. K. ^{[1
]}

Blobe, Gerard ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Durham, NC USA

[2] Free Univ Berlin, Berlin, Germany

[3] Biogen Idec Inc, Cambridge, MA USA

来源：

CANCER RESEARCH | 2012年 / 72卷

关键词：

D O I：

10.1158/1538-7445.AM2012-3548

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

3548

引用

下载

页数：1

共 45 条

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[37] KLF17 empowers TGF-β/Smad signaling by targeting Smad3-dependent pathway to suppress tumor growth and metastasis during cancer progression
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[39] Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer
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[40] Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer
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