Treatment of Radiation-Induced Cognitive Decline in Adult Brain Tumor Patients

被引:36
|
作者
Cramer, Christina K. [1 ]
Cummings, Tiffany L. [2 ]
Andrews, Rachel N. [3 ]
Strowd, Roy [4 ]
Rapp, Stephen R. [5 ,6 ]
Shaw, Edward G. [7 ]
Chan, Michael D. [1 ]
Lesser, Glenn J. [8 ]
机构
[1] Wake Forest Baptist Med Ctr, Dept Radiat Oncol, Med Ctr Blvd, Winston Salem, NC 27157 USA
[2] Wake Forest Baptist Med Ctr, Dept Neurol, Winston Salem, NC 27157 USA
[3] Wake Forest Baptist Med Ctr, Dept Radiat Oncol, Sect Radiat Biol, Med Ctr Blvd, Winston Salem, NC 27157 USA
[4] Wake Forest Baptist Med Ctr, Dept Hematol Oncol, Winston Salem, NC 27157 USA
[5] Wake Forest Sch Med, Dept Psychiat & Behav Med, Med Ctr Blvd, Winston Salem, NC USA
[6] Wake Forest Sch Med, Div Publ Hlth Sci Social Sci & Hlth Policy, Med Ctr Blvd, Winston Salem, NC USA
[7] Wake Forest Baptist Hlth, Memory Counseling Program, Sect Gerontol & Geriatr Med, Sticht Ctr Hlth Aging & Alzheimers Prevent, Med Ctr Blvd, Winston Salem, NC 27157 USA
[8] Wake Forest Baptist Comprehens Canc Ctr, Oncol, Med Neurooncol & Neurooncol Res Program, Med Ctr Blvd, Winston Salem, NC 27157 USA
关键词
Cognition; Brain; Radiation; Neuropsychology; Memory; Attention; NF-KAPPA-B; ALZHEIMERS ASSOCIATION WORKGROUPS; OLIGODENDROCYTE PROGENITOR CELLS; WHITE-MATTER HYPERINTENSITIES; DOUBLE-BLIND; PHASE-III; HIPPOCAMPAL NEUROGENESIS; X-IRRADIATION; NEUROCOGNITIVE FUNCTION; DIAGNOSTIC GUIDELINES;
D O I
10.1007/s11864-019-0641-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Patients with either primary or metastatic brain tumors quite often have cognitive impairment. Maintaining cognitive function is important to brain tumor patients and a decline in cognitive function is generally accompanied by a decline in functional independence and performance status. Cognitive decline can be a result of tumor progression, depression/anxiety, fatigue/sleep dysfunction, or the treatments they have received. It is our opinion that providers treating brain tumor patients should obtain pre-treatment and serial cognitive testing in their patients and offer mitigating and therapeutic interventions when appropriate. They should also support cognition-focused clinical trials. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
引用
收藏
页数:16
相关论文
共 50 条
  • [41] Mitigating radiation-induced cognitive impairment
    Healy, John
    LANCET ONCOLOGY, 2007, 8 (12): : 1055 - 1056
  • [42] Radiation-induced cavernous angioma in an adult
    Rout, Damodar
    Sharmi, Geetha K. M.
    Rajeswaran, R.
    NEUROLOGY INDIA, 2014, 62 (05) : 572 - +
  • [43] Commentary: Postacute Cognitive Rehabilitation for Adult Brain Tumor Patients
    Sefcikova, Viktoria
    Christofi, Gerry
    Samandouras, George
    NEUROSURGERY, 2021, 89 (06) : E295 - E297
  • [44] In Reply: Postacute Cognitive Rehabilitation for Adult Brain Tumor Patients
    Weyer-Jamora, Christina
    Brie, Melissa S.
    Luks, Tracy L.
    Smith, Ellen M.
    Hervey-Jumper, Shawn L.
    Taylor, Jennie W.
    NEUROSURGERY, 2022, 91 (01) : E29 - E29
  • [45] Hyperbaric oxygen therapy attenuates brain radiation-induced cognitive deficits in rats
    Ho, Sheng-Yow
    Lin, Chia-Hui
    Huang, Chien-Cheng
    Lin, Cheng-Hsien
    Lin, Mao-Tsun
    Wang, Ying-Jan
    Ma, Jui-Ti
    Shieh, Li-Tsun
    Chang, Ching-Ping
    Lin, Hung-Jung
    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2025, 22 (02): : 283 - 297
  • [46] Effect of leucovorin on radiation-induced brain injury and tumor radiosensitivity in patients of NPC: A retrospective analysis.
    Liang, ZiBin
    Wang, Siyang
    Yang, Shuai
    Long, Feiyu
    Jiang, Lifeng
    Zou, Yanfei
    Pan, Jinmei
    Lin, Zhong
    Cheng, Zhibin
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [47] Whole Brain Radiation-Induced Cognitive Impairment: Pathophysiological Mechanisms and Therapeutic Targets
    Lee, Yong Woo
    Cho, Hyung Joon
    Lee, Won Hee
    Sonntag, William E.
    BIOMOLECULES & THERAPEUTICS, 2012, 20 (04) : 357 - 370
  • [48] Pre-treatment visualization of predicted radiation-induced acute alopecia in brain tumour patients
    't Ven, Lieke In
    Compter, Inge
    van Eijsden, Kyra
    Zindler, Jaap
    Swinnen, Ans
    de Ruysscher, Dirk
    Rozema, Tom
    Troost, Esther G. C.
    Eekers, Danielle B. P.
    CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY, 2022, 33 : 106 - 111
  • [49] Radiation-induced accelerated aging of the brain vasculature in young adult survivors of childhood brain tumors
    Remes, Tiina Maria
    Suo-Palosaari, Maria Helena
    Koskenkorva, Paivi K. T.
    Sutela, Anna K.
    Toiviainen-Salo, Sanna-Maria
    Arikoski, Pekka M.
    Arola, Mikko O.
    Heikkila, Vesa-Pekka
    Kapanen, Mika
    Lahteenmaki, Paivi Maria
    Lonnqvist, Tuula R., I
    Niiniviita, Hannele
    Pokka, Tytti M-L
    Porra, Liisa
    Riikonen, V. Pekka
    Seppala, Jan
    Sirkia, Kirsti H.
    Vanhanen, Antti
    Rantala, Heikki M. J.
    Harila-Saari, Arja H.
    Ojaniemi, Marja K.
    NEURO-ONCOLOGY PRACTICE, 2020, 7 (04) : 415 - 427
  • [50] Treatment of radiation-induced enterocolitis
    Michalowski, AS
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 38 (04): : 908 - 909