Anatomical aspects, chemical analysis and cytotoxic effect of the essential oil from leaves of Casearia arborea (Salicaceae)

被引：0
|
作者：
Pereira, Flaviane Gomes [1 ]
Marquete, Ronaldo [2 ]
Leite, Kosme Oliveira [3 ]
Cabral, Otavio Versiane [3 ]
May, Barrie [4 ]
Mansur, Elisabeth [5 ]
Moreira, Davyson de Lima [6 ]
机构：
[1] Univ Fed Rio de Janeiro, Programa Posgrad Biotecnol Vegetal & Bioproc, BR-21941 Rio De Janeiro, Brazil
[2] Coordenadoria Recursos Nat CREN, Diretoria Geociencias, IBGE, Rio De Janeiro, Brazil
[3] Inst Fed Educ Ciencia & Tecnol Rio de Janeiro IFR, Rio De Janeiro, Brazil
[4] TreeMod Co, Glen Waverley, Vic 3150, Australia
[5] Univ Estado Rio de Janeiro UERJ, Dept Biol, Rio De Janeiro, Brazil
[6] Fundacao Oswado Cruz Fiocruz, Dept Nat Prod, Inst Tecnol Farmacos, Rio De Janeiro, Brazil
来源：
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS | 2017年 / 16卷 / 02期
关键词：
A549; byciclogermacrene; Casearia arborea; salicaceae; secretory cavities; sesquiterpene; SYLVESTRIS; ANTIOXIDANT; DITERPENES;
D O I：
暂无
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
The genus Casearia (Salicaceae) is found in sub-tropical and tropical regions of the world and comprises about 200 species. In Brazil, there are about 48 species and 12 are registered in the State of Rio de Janeiro; including Casearia arborea (Rich.) Urb. Essential oil was obtained from the fresh leaves by hydrodistillation and analyzed by GC-MS and GC-FID. The cytotoxic effect was determined by WST-1 assay. Chemical analysis of the essential oil revealed a very diversified (n = 37 compounds) volatile fraction composed mainly of non-oxygenated sesquiterpenes (90.2%). These sesquiterpenes included byciclogermacrene (18.7%), germacrene D (12.1%) and alpha-humulene (11.5%). In addition, the essential oil demonstrated cytotoxic effects against A549 tumor cells in the concentration of 4 mu g/mL (EC50) (p < 0.05).
引用
下载
收藏
页码：99 / 109
页数：11
相关论文
共 50 条
  • [41] Chemical composition of the essential oil from the leaves of Eupatorium triplinerve vahl
    Gupta, D
    Charles, R
    Garg, SN
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2004, 16 (05) : 473 - 475
  • [42] Chemical Composition of the Essential Oil From Leaves of Mouriri cearensis Huber
    Gramosa, Nilce V.
    de Freitas, Joao V. B.
    Barreto, Milena B.
    Silveira, Edilberto R.
    Nunes, Edson P.
    Magalhaes, Davi V.
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2009, 21 (05) : 451 - 452
  • [43] Essential Oil from the Leaves of Campomanesia guaviroba (DC.) Kiaersk. (Myrtaceae): Chemical Composition, Antioxidant and Cytotoxic Activity
    Pascoal, Aislan C. R. F.
    Lourenco, Caroline C.
    Sodek, Ladaslav
    Tamashiro, Jorge Y.
    Franchi, Gilberto C., Jr.
    Nowill, Alexandre E.
    Stefanello, Maria Elida A.
    Salvador, Marcos Jose
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2011, 23 (05) : 34 - 37
  • [44] Chemical composition, cytotoxic, and antibacterial activity of the essential oil from Eugenia calycina Cambess. leaves against oral bacteria
    Sousa, Raquel Maria Ferreira
    de Morais, Sergio A. L.
    Vieira, Raissa B. K.
    Napolitani, Danielle R.
    Guzman, Valeska B.
    Moraes, Thais Silva
    Cunha, Luis C. S.
    Martins, Carlos H. G.
    Chang, Roberto
    de Aquino, Francisco J. T.
    do Nascimento, Evandro A.
    de Oliveira, Alberto
    INDUSTRIAL CROPS AND PRODUCTS, 2015, 65 : 71 - 78
  • [45] Chemical Composition, an Antioxidant, Cytotoxic and Microbiological Activity of the Essential Oil from the Leaves of Aeollanthus suaveolens Mart. ex Spreng
    Martins, Rosany Lopes
    Simoes, Ranggel Carvalho
    Rabelo, Erica de Menezes
    Ferreira Farias, Ana Luzia
    Lobato Rodrigues, Alex Bruno
    Ramos, Ryan da Silva
    Fernandes, Joao Batista
    Santos, Lourivaldo da Silva
    da Silva de Almeida, Sheylla Susan Moreira
    PLOS ONE, 2016, 11 (12):
  • [46] Chemical Composition and Anti-Inflammatory, Cytotoxic and Antioxidant Activities of Essential Oil from Leaves of Mentha piperita Grown in China
    Sun, Zhenliang
    Wang, Huiyan
    Wang, Jing
    Zhou, Lianming
    Yang, Peiming
    PLOS ONE, 2014, 9 (12):
  • [47] Chemical Constituents and Cytotoxic Evaluation of Essential Oils from Leaves of Porcelia macrocarpa (Annonaceae)
    da Silva, Erica Biolcati P.
    Matsuo, Alisson L.
    Figueiredo, Carlos R.
    Chaves, Mariana H.
    Sartorelli, Patricia
    Lago, Joao Henrique G.
    NATURAL PRODUCT COMMUNICATIONS, 2013, 8 (02) : 277 - 279
  • [48] Chemical Composition and Cytotoxic Activity of Essential Oil from Myrcia laruotteana Fruits
    Stefanello, Maria Elida A.
    Riva, Dilamara
    Simionatto, Edesio L.
    de Carvalho, Joao E.
    Gois Ruiz, Ana Lucia T.
    Salvador, Marcos J.
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2011, 23 (05) : 7 - 10
  • [49] Chemical composition of essential oil from leaves of Chenopodium ambrosioides from Chandigarh, India
    H. P. Singh
    D. R. Batish
    R. K. Kohli
    S. Mittal
    S. Yadav
    Chemistry of Natural Compounds, 2008, 44 : 378 - 379
  • [50] CHEMICAL COMPOSITION OF ESSENTIAL OIL FROM LEAVES OF Chenopodium ambrosioides FROM CHANDIGARH, INDIA
    Singh, H. P.
    Batish, D. R.
    Kohli, R. K.
    Mittal, S.
    Yadav, S.
    CHEMISTRY OF NATURAL COMPOUNDS, 2008, 44 (03) : 378 - 379
12345