Anatomical aspects, chemical analysis and cytotoxic effect of the essential oil from leaves of Casearia arborea (Salicaceae)

被引：0
|
作者：
Pereira, Flaviane Gomes [1 ]
Marquete, Ronaldo [2 ]
Leite, Kosme Oliveira [3 ]
Cabral, Otavio Versiane [3 ]
May, Barrie [4 ]
Mansur, Elisabeth [5 ]
Moreira, Davyson de Lima [6 ]
机构：
[1] Univ Fed Rio de Janeiro, Programa Posgrad Biotecnol Vegetal & Bioproc, BR-21941 Rio De Janeiro, Brazil
[2] Coordenadoria Recursos Nat CREN, Diretoria Geociencias, IBGE, Rio De Janeiro, Brazil
[3] Inst Fed Educ Ciencia & Tecnol Rio de Janeiro IFR, Rio De Janeiro, Brazil
[4] TreeMod Co, Glen Waverley, Vic 3150, Australia
[5] Univ Estado Rio de Janeiro UERJ, Dept Biol, Rio De Janeiro, Brazil
[6] Fundacao Oswado Cruz Fiocruz, Dept Nat Prod, Inst Tecnol Farmacos, Rio De Janeiro, Brazil
来源：
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS | 2017年 / 16卷 / 02期
关键词：
A549; byciclogermacrene; Casearia arborea; salicaceae; secretory cavities; sesquiterpene; SYLVESTRIS; ANTIOXIDANT; DITERPENES;
D O I：
暂无
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
The genus Casearia (Salicaceae) is found in sub-tropical and tropical regions of the world and comprises about 200 species. In Brazil, there are about 48 species and 12 are registered in the State of Rio de Janeiro; including Casearia arborea (Rich.) Urb. Essential oil was obtained from the fresh leaves by hydrodistillation and analyzed by GC-MS and GC-FID. The cytotoxic effect was determined by WST-1 assay. Chemical analysis of the essential oil revealed a very diversified (n = 37 compounds) volatile fraction composed mainly of non-oxygenated sesquiterpenes (90.2%). These sesquiterpenes included byciclogermacrene (18.7%), germacrene D (12.1%) and alpha-humulene (11.5%). In addition, the essential oil demonstrated cytotoxic effects against A549 tumor cells in the concentration of 4 mu g/mL (EC50) (p < 0.05).
引用
下载
收藏
页码：99 / 109
页数：11
相关论文
共 50 条
  • [31] CHEMICAL COMPOSITION OF ESSENTIAL OIL FROM Atriplex lentiformis LEAVES
    Chouitah, O.
    Meddah, B.
    Aoues, A.
    Sonnet, P.
    CHEMISTRY OF NATURAL COMPOUNDS, 2018, 54 (04) : 772 - 773
  • [32] Chemical Composition, Antimicrobial, Antiparasitic, and Cytotoxic Activities of Rhanterium intermedium Pomel Leaves Essential Oil
    Mahcene, Salem
    Elhouiti, Fatiha
    Mennai, Imad
    Pinto, Diana C. G. A.
    Tahri, Djilali
    Ouinten, Mohamed
    Yousfi, Mohamed
    ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING, 2023, 48 (06) : 7337 - 7347
  • [33] Chemical Composition, Antimicrobial, Antiparasitic, and Cytotoxic Activities of Rhanterium intermedium Pomel Leaves Essential Oil
    Salem Mahcene
    Fatiha Elhouiti
    Imad Mennai
    Diana C. G. A. Pinto
    Djilali Tahri
    Mohamed Ouinten
    Mohamed Yousfi
    Arabian Journal for Science and Engineering, 2023, 48 : 7337 - 7347
  • [34] Chemical characterization and synergistic antibiotic activity of volatile compounds from the essential oil of Vanillosmopsis arborea
    N. K. A. Santos
    H. D. M. Coutinho
    G. S. B. Viana
    Fabíola F. G. Rodrigues
    José G. M. Costa
    Medicinal Chemistry Research, 2011, 20 : 637 - 641
  • [35] Chemical composition, antimicrobial, antioxidant and cytotoxic activity of the essential oil from the leaves of Acanthopanax leucorrhizus (Oilv.) Harms
    Hu, Haobin
    Zheng, Xudong
    Hu, Huaisheng
    ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2012, 34 (02) : 618 - 623
  • [36] Chemical characterization and synergistic antibiotic activity of volatile compounds from the essential oil of Vanillosmopsis arborea
    Santos, N. K. A.
    Coutinho, H. D. M.
    Viana, G. S. B.
    Rodrigues, Fabiola F. G.
    Costa, Jose G. M.
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (05) : 637 - 641
  • [37] Chemical Composition and Effect of Hydrodistillation Times on the Yield of Essential Oil from Eugenia pyriformis Leaves
    Sa Durazzini, Ana Maria
    Marquezini Machado, Carlos Henrique
    Fernandes, Cassia Cristina
    Dantas Miranda, Mayker Lazaro
    ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY, 2019, 11 (05): : 334 - 338
  • [38] Multivariate analysis of the chemical composition of the essential oil from leaves of Melaleuca quinquenervia growing in Cuba
    Luisa Morales-Rico, Carmen
    Marrero-Delange, David
    Luis Gonzalez-Canavaciolo, Victor
    Quintana-Ramos, Felipe
    Gonzalez-Camejo, Ivan
    Dago-Morales, Angel
    BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS, 2015, 14 (05): : 374 - 384
  • [39] Essential Oil from the Leaves of Annona vepretorum: Chemical Composition and Bioactivity
    Costa, Emmanoel Vilaca
    Dutra, Livia Macedo
    de Lima Nogueira, Paulo Cesar
    de Souza Moraes, Valeria Regina
    Salvador, Marcos Jose
    Gonzaga Ribeiro, Luis Henrique
    Gadelha, Fernanda Ramos
    NATURAL PRODUCT COMMUNICATIONS, 2012, 7 (02) : 265 - 266
  • [40] Chemical Composition of the Essential Oil from Jasminum pubescens Leaves and Flowers
    Temraz, Abeer
    Cioni, Pier Luigi
    Flamini, Guido
    Braca, Alessandra
    NATURAL PRODUCT COMMUNICATIONS, 2009, 4 (12) : 1729 - 1732
12345