N-H Spin-Spin Couplings: Probing Hydrogen Bonds in Proteins

被引：14

作者：

Xiang, Sheng-Qi ^{[1
]}

Narayanan, Raghavendran L. ^{[1
]}

Becker, Stefan ^{[1
]}

Zweckstetter, Markus ^{[1
,2
]}

机构：

[1] Max Planck Inst Biophys Chem, D-37077 Gottingen, Germany

[2] Deutsch Zentrum Neurodegenerat Erkrankungen DZNE, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 12期

关键词：

amides; coupling constants; hydrogen bonds; NMR spectroscopy; proteins; SCALAR COUPLINGS; DIPOLAR COUPLINGS; N-15-H-1; SCALAR; CHEMICAL-SHIFTS; CONSTANTS; UBIQUITIN; BINDING; TAU;

D O I：

10.1002/anie.201209641

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sensitive information: Hydrogen bonds stabilize protein structures and are critical for many chemical and biological phenomena. NMR studies found that the one-bond 1H-15N scalar coupling constant is increased by up to 1.6 Hz when a hydrogen bond is formed. These coupling constants therefore provide a sensitive tool for studying protein structure. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3525 / 3528

页数：4

共 50 条

[31] Spin-spin couplings of tempol nitroxyl radicals in organic solvents
Nikonova, SI
Paikin, OM
[J]. CHEMICAL PHYSICS REPORTS, 1998, 17 (05): : 871 - 881
[32] ON SPIN-SPIN COUPLING BETWEEN C-13 AND H SEPARATED BY 2 BONDS
JAMESON, CJ
DAMASCO, MC
[J]. MOLECULAR PHYSICS, 1970, 18 (04) : 491 - &
[33] KRAMERS MECHANISM OF INDIRECT SPIN-SPIN COUPLINGS OF NUCLEI IN CRYSTALS
MOROZ, NK
KOZLOVA, SG
GABUDA, SP
[J]. JOURNAL OF STRUCTURAL CHEMISTRY, 1993, 34 (02) : 239 - 243
[34] INDIRECT NUCLEAR SPIN-SPIN COUPLINGS IN SATURATED HYDROCARBON MOLECULES
HIROIKE, E
[J]. JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 1960, 15 (02) : 270 - 284
[35] LINEAR ELECTRIC FIELD DEPENDENCE OF 13C-H NUCLEAR SPIN-SPIN COUPLINGS
RAYNES, WT
SUTHERLEY, TA
[J]. MOLECULAR PHYSICS, 1969, 17 (05) : 547 - +
[36] Spin-spin coupling across intermolecular F-Cl... N halogen bonds
Del Bene, Janet E.
Alkorta, Ibon
Elguero, Jose
[J]. JOURNAL OF PHYSICAL CHEMISTRY A, 2008, 112 (34): : 7925 - 7929
[37] N-N spin-spin coupling constants [2hJ(15N-15N)] across N-H•••N hydrogen bonds in neutral complexes:: To what extent does the bonding at the nitrogens influence 2hJN-N?
Del Bene, JE
Bartlett, RJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (42) : 10480 - 10481
[38] Using spin-spin coupling constants to probe hydrogen bonds in proton-bound complexes
Del Bene, Janet E.
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233 : 323 - 323
[39] Probing the proton-transfer coordinate of complexes with F-H•••P hydrogen bonds using one- and two-bond spin-spin coupling constants
Del Bene, Janet E.
Elguero, Jose
[J]. MAGNETIC RESONANCE IN CHEMISTRY, 2007, 45 (09) : 714 - 719
[40] Two-bond 19F-15N spin-spin coupling constants (2hJF-N) across F-H•••N hydrogen bonds
Del Bene, JE
Perera, SA
Bartlett, RJ
Yáñez, M
Mó, O
Elguero, J
Alkorta, I
[J]. JOURNAL OF PHYSICAL CHEMISTRY A, 2003, 107 (17): : 3121 - 3125

← 1 2 3 4 5 →