Allosteric regulation of the ligand-binding ability of Zn-porphyrin by metal complexation

被引:5
|
作者
Kozaki, Masatoshi [1 ]
Ninomiya, Yoshikazu [1 ]
Suzuki, Shuichi [1 ]
Okada, Keiji [1 ]
机构
[1] Osaka City Univ, Grad Sch Sci, Sumiyoshi Ku, Osaka 5588585, Japan
关键词
Allosteric system; Porphyrin; Bipyridine; Axial ligand; Sonogashira coupling; SYSTEMS; PSEUDOCRYPTAND; CASCADE;
D O I
10.1016/j.tetlet.2013.04.130
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Zn-porphyrin with bipyridyl units at the ends of a conjugated chain, in addition to two alkyl side chains, was prepared as an artificial allosteric system. The axial ligand-binding ability of the compound was considerably reduced by the formation of a Fe(bpy)(3)-type complex. The degree of the allosteric suppression strongly depended on both alkyl chain length and the steric demand of the pyridyl ligand. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3658 / 3661
页数:4
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