Comparison of the Abbott m2000 RealTime CT Assay and the Cepheid GeneXpert CT/NG Assay to the Roche Amplicor CT Assay for Detection of Chlamydia trachomatis in Ocular Samples from Tanzania

被引：32
|
作者：
Dize, Laura [1 ]
West, Sheila [1 ]
Williams, James A. [2 ]
Van der Pol, Barbara [2 ,3 ]
Quinn, Thomas C. [1 ,4 ]
Gaydos, Charlotte A. [1 ]
机构：
[1] Johns Hopkins Univ, Baltimore, MD 21218 USA
[2] Indiana Univ Sch Med, Indianapolis, IN USA
[3] Indiana Univ, Sch Publ Hlth, Bloomington, IN USA
[4] NIAID, Div Intramural Res, NIH, Bethesda, MD 20892 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2013年 / 51卷 / 05期
基金：
美国国家卫生研究院;
关键词：
MASS TREATMENT; INFECTION;
D O I：
10.1128/JCM.00519-13
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The GeneXpert CT/NG assay (GeneXpert) and the Abbott m2000 RealTime CT (m2000) assay were compared to Amplicor for detecting ocular Chlamydia trachomatis. Discordant specimens were tested by the Aptima CT assay. The m2000 assay sensitivity was 100% (95% confidence interval [CI], 90% to 100%), and specificity was 98.46% (95% CI, 95.2% to 99.2%); GeneXpert sensitivity was 100% (95% CI, 90% to 100%), and specificity was 100% (95% CI, 98.1% to 100%). The m2000 and GeneXpert assays appear to perform as well as the Amplicor assay.
引用
收藏
页码：1611 / 1613
页数：3
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