Synthetic studies on breviones: construction of the CDE ring system

被引：16
|
作者：
Takikawa, H
Hirooka, M
Sasaki, M
机构：
[1] Kobe Univ, Dept Biofunct Chem, Nada Ku, Kobe, Hyogo 6578501, Japan
[2] Kobe Univ, Ctr Cooperat Res & Dev, Nada Ku, Kobe, Hyogo 6578501, Japan
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 09期
关键词：
diterpenoids; allelopathic agents; tandem reaction; palladium catalyst;
D O I：
10.1016/S0040-4039(02)00081-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Breviones A-E (1-5), allelopathic agents isolated from Penicillium brevicompactum Dierckx, are structurally unique pentacyclic or hexacyclic diterpenoid derivatives. The synthesis of a structurally simplified model compound (8), corresponding to the characteristic spiro-fused CDE ring portion of 1-4, was accomplished by employing sequential, double nucleophilic substitution reactions as the key steps. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码：1713 / 1716
页数：4
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