Two New Triterpenoids from the Roots of Codonopsis pilosula

被引：18
|
作者：
Zheng, Tao [1 ,2 ]
Cheng, Li-Zhi [3 ]
Yan, Yong-Ming [3 ]
Liu, Bao-Hua [3 ]
Qin, Fu-Ying [1 ,3 ]
Xu, Fu-Rong [2 ]
Cheng, Yong-Xian [1 ,2 ,3 ,4 ]
机构：
[1] Yunnan Univ Tradit Chinese Med, Coll Pharm, Kunming 650504, Yunnan, Peoples R China
[2] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
[3] Shenzhen Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Shenzhen 518060, Peoples R China
[4] Henan Univ Chinese Med, Coll Pharm, Zhengzhou 450008, Henan, Peoples R China
来源：
MOLECULES | 2018年 / 23卷 / 02期
关键词：
Codonopsis pilosula; pseudolarolides; triterpenoids; SIRT1; PSEUDOLARIX-KAEMPFERI; PYRROLIDINE ALKALOIDS; STEREOCHEMISTRY; DILACTONE; LACTONES; SIRT1;
D O I：
10.3390/molecules23020383
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Pseudolarolides U and V, two new triterpenoids, and four biogenetically related compounds, pseudolarolides E, F, K, and P were isolated from the roots of Codonopsis pilosula (Campanulaceae). Their structures were determined by spectroscopic data. The regulation of Sirtuin 1 (SIRT1) activity by all the isolated compounds was evaluated.
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页数：7
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