A mitochondria-targeted and FRET-based ratiometric fluorescent probe for detection of SO2 derivatives in water

被引：50

作者：

Zhang, Dongsheng ^{[1
]}

Liu, Aikun ^{[1
]}

Ji, Ruixue ^{[1
]}

Dong, Jian ^{[1
]}

Ge, Yanqing ^{[1
]}

机构：

[1] Taishan Med Univ, Sch Chem & Pharmaceut Engn, Tai An 271016, Shandong, Peoples R China

来源：

ANALYTICA CHIMICA ACTA | 2019年 / 1055卷

关键词：

pyrido[1,2-a]benzimidazole; Hemicyanine; FRET; Bioimaging; Mitochondria; SULFUR-DIOXIDE DERIVATIVES; HYDROGEN-SULFIDE; SELECTIVE DETECTION; RAPID DETECTION; IN-VIVO; BISULFITE; CHEMOSENSORS; CYSTEINE;

D O I：

10.1016/j.aca.2018.12.042

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A mitochondria-targeted ratiometric fluorescent probe based on the fluorophore pyrido[1,2-a]benzimidazole was developed. It showed high sensitivity and selectivity toward SO2 derivatives in water. The probe was also successfully applied to detect intrinsically generated SO2 derivatives in living glioma cells, which may be helpful in ascertaining the biological roles of SO2 in mitochondria. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：133 / 139

页数：7

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