A mitochondria-targeted ratiometric fluorescent probe for detection of SO2 derivatives in living cells and in vivo

被引：19

作者：

Yang, Xueli ^{[1
]}

Yang, Yutao ^{[1
,2
]}

Zhou, Tingting ^{[1
]}

Jin, Ming ^{[1
]}

Jing, Xuequan ^{[1
]}

Miao, Cai Hong ^{[1
]}

Li, Wei ^{[1
]}

机构：

[1] Hebei Univ, Coll Chem & Environm Sci, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Peoples R China

[2] Hebei Univ, Key Lab Chem Biol Hebei Prov, Baoding 071002, Peoples R China

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 2019年 / 372卷

基金：

中国国家自然科学基金;

关键词：

SO2; derivatives; Mitochondria-targeted; Near-infrared fluorescent probe; Colorimetric; Ratiometric; SULFUR-DIOXIDE DERIVATIVES; SELECTIVE DETECTION; ION CHROMATOGRAPHY; BIOLOGICAL SO2; BISULFITE; SULFITE; FOOD; CHEMILUMINESCENCE; METABOLISM; PROGRESS;

D O I：

10.1016/j.jphotochem.2018.12.020

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new near-infrared (NIR) fluorescent probe for colorimetric and ratiometric detection of SO2 derivatives was developed based on conjugated hybrid coumarin-hemicyanine. The probe can detect HSO3-/SO32- in HEPES buffer (10 mM, pH 7.4, with 10% DMF, v/v) with a large emission shift (259 nm). Importantly, it was successfully used for fluorescence imaging of endogenous bisulfite in BT-474 cells and zebrafish.

引用

页码：212 / 217

页数：6

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