There are five cryogenic plants at Jefferson Lab which support the LINAC, experiment hall end-stations and test facility. The majority of JLab's helium inventory, which is around 15 tons, is allocated in the LINAC cryo-modules, with the majority of the balance of helium distributed at the cryogenic-plant level mainly as stored gas and liquid for stable operation. Due to the organic evolution of the five plants and independent actions within the experiment halls, the traditional inventory management strategy suffers from rapid identification of potential leaks. This can easily result in losses many times higher than the normally accepted (average) loss rate. A real-time program to quickly identify potential excessive leakage was developed and tested. This program was written in MATLAB (c) for portability, easy diagnostics and modification. It interfaces directly with EPICS to access the cryogenic system state, and with and NIST REFPROP (c) for real fluid properties. This program was validated against the actual helium offloaded into the system. The present paper outlines the details of the inventory monitoring program, its validation and a sample of the achieved results.