Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent

被引：83
|
作者：
Gao, Bing [1 ]
Zhao, Yanchuan [1 ]
Hu, Jingyu [1 ]
Hu, Jinbo [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2015年 / 2卷 / 02期
基金：
中国国家自然科学基金;
关键词：
NUCLEOPHILIC TRIFLUOROMETHYLATION; EFFICIENT SYNTHESIS; DERIVATIVES; 1,1-DIFLUORO-1-ALKENES; OLEFINATION; ALDEHYDES; ALKENES; KETONES; FLUOROALKYLATIONS; DIFLUOROALKENES;
D O I：
10.1039/c4qo00291a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This tutorial account describes a robust carbonyl gem-difluoroolefination reagent, difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H), developed by our group, recently. The guidelines for its laboratory preparation and application are presented in detail for potential users.
引用
收藏
页码：163 / 168
页数：6
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