Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent

被引：83
|
作者：
Gao, Bing [1 ]
Zhao, Yanchuan [1 ]
Hu, Jingyu [1 ]
Hu, Jinbo [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2015年 / 2卷 / 02期
基金：
中国国家自然科学基金;
关键词：
NUCLEOPHILIC TRIFLUOROMETHYLATION; EFFICIENT SYNTHESIS; DERIVATIVES; 1,1-DIFLUORO-1-ALKENES; OLEFINATION; ALDEHYDES; ALKENES; KETONES; FLUOROALKYLATIONS; DIFLUOROALKENES;
D O I：
10.1039/c4qo00291a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This tutorial account describes a robust carbonyl gem-difluoroolefination reagent, difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H), developed by our group, recently. The guidelines for its laboratory preparation and application are presented in detail for potential users.
引用
收藏
页码：163 / 168
页数：6
相关论文
共 50 条
  • [31] Synthesis of the [MeAl(2-py)3]- anion and its application as a stable and mild pyridyl-transfer reagent (2-py=2-pyridyl)
    García, F
    Hopkins, AD
    Kowenicki, RA
    McPartlin, M
    Rogers, MC
    Wright, DS
    ORGANOMETALLICS, 2004, 23 (16) : 3884 - 3890
  • [32] (2-Pyridyl)phenyl methanol: a new reagent for metal-free reduction of nitro aromatic compounds
    Giomi, Donatella
    Alfini, Renzo
    Brandi, Alberto
    TETRAHEDRON, 2011, 67 (01) : 167 - 172
  • [33] MECHANISTIC AND KINETIC-STUDIES ON THE POLYMERIZATION OF STYRENE INITIATED BY DIMETHYL SULFONIUM 2-PYRIDYL CARBONYL METHYLIDE
    BHATNAGAR, U
    SRIVASTAVA, AK
    POLYMER INTERNATIONAL, 1991, 25 (01) : 13 - 17
  • [34] ACETALS AND KETALS OF 2-(2-PYRIDYL)PROPANE-1,3-DIOL NOVEL PROTECTION FOR CARBONYL GROUPS
    KATRITZKY, AR
    FAN, WQ
    LI, QL
    TETRAHEDRON LETTERS, 1987, 28 (11) : 1195 - 1198
  • [35] TERT-BUTYL 2-PYRIDYL CARBONATE - A USEFUL REAGENT FOR TERT-BUTOXYCARBONYLATION OF AMINO-ACIDS
    KIM, S
    LEE, JI
    CHEMISTRY LETTERS, 1984, (02) : 237 - 238
  • [36] Triruthenium and triosmium carbonyl cluster complexes containing deprotonated di(2-pyridyl)amine in unusual coordination modes
    Cabeza, JA
    del Río, I
    García-Granda, S
    Riera, V
    Suárez, M
    ORGANOMETALLICS, 2002, 21 (12) : 2540 - 2543
  • [37] An Easy One-Pot Synthesis of Diverse 2,5-Di(2-pyridyl)pyrroles: A Versatile Entry Point to Metal Complexes of Functionalised, Meridial and Tridentate 2,5-Di(2-pyridyl)pyrrolato Ligands
    McSkimming, Alex
    Diachenko, Vera
    London, Rachel
    Olrich, Kiara
    Onie, C. Jessica
    Bhadbhade, Mohan M.
    Bucknall, Martin P.
    Read, Roger W.
    Colbran, Stephen B.
    CHEMISTRY-A EUROPEAN JOURNAL, 2014, 20 (36) : 11445 - 11456
  • [38] SYNTHESIS AND CHARACTERIZATION OF RE(I) CARBONYL-COMPLEXES BOUND WITH THE BRIDGING LIGAND 2,3-(2-PYRIDYL)PYRAZINE
    RUMINSKI, RR
    CAMBRON, RT
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1990, 199 : 85 - INOR
  • [39] O,O′-Di(2-pyridyl) thiocarbonate as an efficient reagent for the preparation of carboxylic esters from highly hindered alcohols
    Saitoh, K
    Shiina, I
    Mukaiyama, T
    CHEMISTRY LETTERS, 1998, (07) : 679 - 680
  • [40] Syntheses, crystal structures, and characterization of heteronuclear complexes based on a versatile ligand with both acetylacetonate and bis(2-pyridyl) units
    Xiong, Jing
    Sun, Lei
    Kang, Ling-Chen
    Liu, Wei
    Zheng, You-Xuan
    Zuo, Jing-Lin
    You, Xiao-Zeng
    INORGANICA CHIMICA ACTA, 2011, 376 (01) : 36 - 43
12345