In Vitro Effects of Molecular Nanosomal Hybrid Compositions with Oxidized Dextrans, Conjugated with Isonicotinic Acid Hydrazine on Peritoneal Macrophages

被引：4

作者：

Shkurupy, V. A. ^{[1
]}

Arkhipov, S. A. ^{[1
]}

Tkachev, V. O. ^{[1
]}

Troitsky, A. V. ^{[1
]}

Luzgina, N. G. ^{[1
]}

Zaikovskaja, M. V. ^{[1
]}

Gulyaeva, E. P. ^{[1
]}

Bistrova, T. N. ^{[1
]}

Ufimtceva, E. G. ^{[1
]}

机构：

[1] Russian Acad Med Sci, Siberian Div, Ctr Clin & Expt Med, Novosibirsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2008年 / 146卷 / 05期

关键词：

oxidized dextranes; isonicotinic acid hydrazide; nanoliposomes; peritoneal macrophages;

D O I：

10.1007/s10517-009-0363-z

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The effects of molecular nanosomal hybrid compositions consisting of nanoliposomes with oxidized dextrans (mol. weights 35 and 60 kDa) conjugated with isonicotinic acid hydrazine (dextrazides) on peritoneal macrophages were studied in vitro. Incubation of peritoneal cells with molecular nanosomal hybrid compositions modified the immunological phenotype of macrophage populations, which reflected an increase in their functional activity. Molecular nanosomal hybrid compositions containing dextrazide with 60-kDa dextran more effectively activated macrophages.

引用

页码：627 / 629

页数：3

共 14 条

[1] In Vitro Effects of Molecular Nanosomal Hybrid Compositions with Oxidized Dextrans, Conjugated with Isonicotinic Acid Hydrazine on Peritoneal Macrophages
V. A. Shkurupy
S. A. Arkhipov
V. O. Tkachev
A. V. Troitsky
N. G. Luzgina
M. V. Zaikovskaja
E. P. Gulyaeva
T. N. Bistrova
E. G. Ufimtceva
Bulletin of Experimental Biology and Medicine, 2008, 146 : 627 - 629
[2] Phagocytosis of Hybrid Molecular Nanosomal Compositions Containing Oxidized Dextrans Conjugated with Isonicotinic Acid Hydrazide by Macrophages
Shkurupy, V. A.
Arkhipov, S. A.
Troitsky, A. V.
Luzgina, N. G.
Zaikovskaja, M. V.
Ufimceva, E. G.
Iljine, D. A.
Akhramenko, E. S.
Gulyaeva, E. P.
Bistrova, T. N.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2009, 148 (06) : 874 - 876
[3] Phagocytosis of Hybrid Molecular Nanosomal Compositions Containing Oxidized Dextrans Conjugated with Isonicotinic Acid Hydrazide by Macrophages
V. A. Shkurupy
S. A. Arkhipov
A. V. Troitsky
N. G. Luzgina
M. V. Zaikovskaja
E. G. Ufimceva
D. A. Iljine
E. S. Akhramenko
E. P. Gulyaeva
T. N. Bistrova
Bulletin of Experimental Biology and Medicine, 2009, 148 : 874 - 876
[4] Effects of Molecular Liposomal Hybrid Compositions with Oxidized Dextrans and Isonicotinic Acid Hydrazide on Production of Granulocytic Macrophage Colony-Stimulating Factor by Macrophages
V. A. Shkurupy
S. A. Arkhipov
A. V. Troitsky
N. G. Luzgina
M. V. Zaikovskaja
E. G. Ufimceva
D. A. Iljine
E. S. Akhramenko
E. P. Gulyaeva
T. N. Bistrova
Bulletin of Experimental Biology and Medicine, 2009, 148 : 710 - 712
[5] Effects of Molecular Liposomal Hybrid Compositions with Oxidized Dextrans and Isonicotinic Acid Hydrazide on Production of Granulocytic Macrophage Colony-Stimulating Factor by Macrophages
Shkurupy, V. A.
Arkhipov, S. A.
Troitsky, A. V.
Luzgina, N. G.
Zaikovskaja, M. V.
Ufimceva, E. G.
Iljine, D. A.
Akhramenko, E. S.
Gulyaeva, E. P.
Bistrova, T. N.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2009, 148 (04) : 710 - 712
[6] Phagocytic Activity of Macrophages against Liposomes with Conjugates of Oxidized Dextrans and Isonicotinic Acid Hydrazide during Modeling of Phagocytosis Disturbances In Vitro
Arkhipov, S. A.
Shkurupy, V. A.
Troitsky, A. V.
Luzgina, N. G.
Ufimceva, E. G.
Zaikovskaja, M. V.
Iljine, D. A.
Akhramenko, E. S.
Gulyaeva, E. P.
Bistrova, T. N.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2009, 148 (04) : 689 - 691
[7] Phagocytic Activity of Macrophages against Liposomes with Conjugates of Oxidized Dextrans and Isonicotinic Acid Hydrazide during Modeling of Phagocytosis Disturbances In Vitro
S. A. Arkhipov
V. A. Shkurupy
A. V. Troitsky
N. G. Luzgina
E. G. Ufimceva
M. V. Zaikovskaja
D. A. Iljine
E. S. Akhramenko
E. P. Gulyaeva
T. N. Bistrova
Bulletin of Experimental Biology and Medicine, 2009, 148 : 689 - 691
[8] Effects of Liposomal Compositions with Oxidized Dextrans on Functional Activity of U937 Macrophage-Like Cells In Vitro
Kozhin, P. M.
Chechushkov, A. V.
Zaitseva, N. S.
Lemza, A. E.
Men'shchikova, E. B.
Troitskii, A. V.
Shkurupy, V. A.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2015, 160 (01) : 57 - 60
[9] Effects of Liposomal Compositions with Oxidized Dextrans on Functional Activity of U937 Macrophage-Like Cells In Vitro
P. M. Kozhin
A. V. Chechushkov
N. S. Zaitseva
A. E. Lemza
E. B. Men’shchikova
A. V. Troitskii
V. A. Shkurupy
Bulletin of Experimental Biology and Medicine, 2015, 160 : 57 - 60
[10] Effects　of　10-hydroxy-2-decenoic　acid　on　phagocytosis　and　cytokines　production　of　peritoneal　macrophages　in　vitro
王国燕
林志彬
ActaPharmacologicaSinica, 1997, (02) : 85 - 87

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