Effects　of　10-hydroxy-2-decenoic　acid　on　phagocytosis　and　cytokines　production　of　peritoneal　macrophages　in　vitro

被引：0
|
作者：
王国燕 [1 ]
林志彬 [1 ]
机构：
[1] 北京医科大学基础医学院药理学系
来源：
ActaPharmacologicaSinica | 1997年 / 02期
关键词：
10-羟基-2-癸烯酸; 腹腔巨噬细胞; 肿瘤坏死因子; 白细胞介素-1; 培养的细胞;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
研究１０羟基２癸烯酸（ＨＤＡ）在体外对大鼠腹腔巨噬细胞活性的影响．方法：测定ＨＤＡ对吞噬活性，抗癌细胞因子ＴＮＦ和ＩＬ１产生的影响．结果：ＨＤＡ（５０，１００ｍｇ·Ｌ－１）能增强巨噬细胞吞噬活性，ＨＤＡ在５０，１００，２００ｍｇ·Ｌ－１时能促进ＴＮＦ和ＩＬ１产生．结论：ＨＤＡ上调巨噬细胞的吞噬活性，促进ＴＮＦ和ＩＬ１产生，在抗肿瘤和免疫调节中起一定作用．
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页码：85 / 87
页数：3
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