Label-Free Pathogen Detection with Sensor Chips Assembled from Peptide Nanotubes

被引：58
|
作者：
de la Rica, Roberto [1 ]
Mendoza, Ernest [2 ]
Lechuga, Laura M. [2 ]
Matsui, Hiroshi [1 ]
机构：
[1] CUNY Hunter Coll, Dept Chem & Biochem, New York, NY 10065 USA
[2] ETSE, CSIC ICN, Res Ctr Nanosci & Nanotechnol CIN2, Nanobiosensors & Mol Nanobiophys Grp, Barcelona 08193, Spain
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 50期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
bionanotechnology; peptide nanotubes; self-assembly; sensors; viruses;
D O I：
10.1002/anie.200804299
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) A robust viral sensor was developed by bridging a pair of gold electrodes with antibody-coated peptide nanotubes. The nanotubes concentrated the target virus on their surface by molecular recognition between the antibody and the virus (see picture). The nanotubes fit perfectly within the electric field line distribution to enable the extremely sensitive impedimetric detection of viral particles. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：9752 / 9755
页数：4
相关论文
共 50 条
  • [41] microfluidic laser scattering sensor for label-free detection of waterborne pathogens
    Huang, Wei
    Yang, Limei
    Li, Feng
    HYPERSPECTRAL REMOTE SENSING APPLICATIONS AND ENVIRONMENTAL MONITORING AND SAFETY TESTING TECHNOLOGY, 2016, 10156
  • [42] Directly immobilized DNA sensor for label-free detection of herpes virus
    Tam, P. D.
    Tuan, M. A.
    Aarnink, Tom
    Chien, N. D.
    2008 INTERNATIONAL SPECIAL TOPIC CONFERENCE ON INFORMATION TECHNOLOGY AND APPLICATIONS IN BIOMEDICINE, VOLS 1 AND 2, 2008, : 77 - +
  • [43] Label-free detection of allergens in milk using a metallic mesh sensor
    Yoshida, Hisa
    Ogawa, Yuichi
    Hayashi, Shin'ichiro
    Otani, Chiko
    Kawase, Kodo
    Journal of the Illuminating Engineering Institute of Japan (Shomei Gakkai Shi), 2009, 93 (08): : 487 - 491
  • [44] An Ultrasensitive Field Effect Charge Sensor for Label-free Biomolecule Detection
    Shao, Shiqian
    Wang, Yi
    2009 LASERS & ELECTRO-OPTICS & THE PACIFIC RIM CONFERENCE ON LASERS AND ELECTRO-OPTICS, VOLS 1 AND 2, 2009, : 1270 - 1271
  • [45] Label-free Guided Mode Resonance Sensor for Detection of Glycated Hemoglobin
    Seeleang, Boonrasri
    Promptmas, Chamras
    Boonruang, Sakoolkan
    Mohammed, Waleed S.
    Jolivot, Romuald
    2017 CONFERENCE ON LASERS AND ELECTRO-OPTICS PACIFIC RIM (CLEO-PR), 2017,
  • [46] Label and label-free based surface-enhanced Raman scattering for pathogen bacteria detection: A review
    Liu, Yu
    Zhou, Haibo
    Hu, Ziwei
    Yu, Guangxia
    Yang, Danting
    Zhao, Jinshun
    BIOSENSORS & BIOELECTRONICS, 2017, 94 : 131 - 140
  • [47] Label-free and facile electrochemical biosensing using carbon nanotubes for malondialdehyde detection
    Yuan, Ling
    Lan, Yaqian
    Han, Min
    Bao, Jianchun
    Tu, Wenwen
    Dai, Zhihui
    ANALYST, 2013, 138 (11) : 3131 - 3134
  • [48] Label-free biomarker detection from whole blood
    Stern E.
    Vacic A.
    Rajan N.K.
    Criscione J.M.
    Park J.
    Ilic B.R.
    Mooney D.J.
    Reed M.A.
    Fahmy T.M.
    Nature Nanotechnology, 2010, 5 (2) : 138 - 142
  • [49] Label-free biomarker detection from whole blood
    Stern, Eric
    Vacic, Aleksandar
    Rajan, Nitin K.
    Criscione, Jason M.
    Park, Jason
    Ilic, Bojan R.
    Mooney, David J.
    Reed, Mark A.
    Fahmy, Tarek M.
    NATURE NANOTECHNOLOGY, 2010, 5 (02) : 138 - 142
  • [50] Label-free electrical detection of DNA hybridization using carbon nanotubes and graphene
    Fu, Dongliang
    Li, Lain-Jong
    NANO REVIEWS & EXPERIMENTS, 2010, 1 (01):
12345