Synthesis and antibacterial activity of some new hydrazones

被引：20
|
作者：
Rudrapal, M. [1 ]
Satyanandam, R. Siva [1 ]
Swaroopini, T. Sri [1 ]
Lakshmi, T. Naga [1 ]
Jaha, S. Kamar [1 ]
Zaheera, S. [1 ]
机构：
[1] Aditya Inst Pharmaceut Sci & Res, Surampalem 533437, Andhra Pradesh, India
来源：
MEDICINAL CHEMISTRY RESEARCH | 2013年 / 22卷 / 06期
关键词：
Hydrazone; Azomethine; Heteroaromatic scaffold; Antibacterial; DERIVATIVES;
D O I：
10.1007/s00044-012-0278-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
New hydrazone derivatives were synthesized by the condensation of some selected heteroaromatic hydrazines with appropriate aromatic ketones at high temperature (100 A degrees C). The structures of the synthesized compounds were established by elemental (CHN) and spectral (IR, (HNMR)-H-1, and Mass) analysis. The synthesized compounds were screened for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Proteus mirabilis) activities, which reveal that all the compounds possess activity against all the tested organisms.
引用
收藏
页码：2840 / 2846
页数：7
相关论文
共 50 条
  • [41] Electrochemical behavior of some potential antibacterial hydrazones
    Jain, R
    Shrivastava, MK
    Gupta, S
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2002, 79 (10) : 837 - 839
  • [42] SYNTHESIS OF SOME AZOMETHINES AND HYDRAZONES HAVING EXPECTED ANTITUBERCULOUS ACTIVITY
    SOLIMAN, R
    CHAABAN, I
    PHARMAZIE, 1979, 34 (02): : 73 - 74
  • [43] Transformation of 5α-Pregnenolone Into Some Hydrazones: Synthesis and Biological Activity
    Nadaraia, N. Sh.
    Barbakadze, N. N.
    Kvaratskhelia, T. B.
    Kakhabrishvili, M. L.
    Legault, J.
    Mulkidzhanyan, K. G.
    Mshvildadze, V. D.
    CHEMISTRY OF NATURAL COMPOUNDS, 2025, : 300 - 305
  • [44] SYNTHESIS AND EVALUATION OF ANTIOXIDANT ACTIVITY OF SOME HYDRAZONES WITH XANTHINE STRUCTURE
    Constantin, Sandra
    Panzariu, Andreea
    Vasincu, Ioana
    Apotrosoaei, Maria
    Confederat, Luminita
    Buron, F.
    Routier, S.
    Profire, Lenuta
    MEDICAL-SURGICAL JOURNAL-REVISTA MEDICO-CHIRURGICALA, 2015, 119 (03): : 910 - 916
  • [45] SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF THIOSEMICARBAZONES AND HYDRAZONES DERIVED FROM INDANONE-1
    MISRA, VS
    VARMA, RS
    AGARWAL, S
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1975, 52 (10) : 981 - 982
  • [46] Synthesis and in vitro anticancer activity of some new hydrazide-hydrazones derived from articaine
    Karaku, Sevgi
    Tok, Fatih
    Abas, Burcin Irem
    Tutuncu, Elif
    Kalkan, Nigar Kubra
    Turk, Sevda
    Cevik, Ozge
    JOURNAL OF RESEARCH IN PHARMACY, 2024, 28 (06): : 1901 - 1910
  • [47] Synthesis and evaluation of antibacterial activity of hydrazones of 1,4-quinoxaline derivatives
    Siddiqui, AA
    Khan, SA
    Rehman, ZU
    ASIAN JOURNAL OF CHEMISTRY, 2003, 15 (01) : 47 - 48
  • [48] Synthesis and Antimicrobial Activity of New Pyrimidine-Hydrazones
    Kaplancikli, Zafer Asim
    Yurttas, Leyla
    Turan-Zitouni, Gulhan
    Ozdemir, Ahmet
    Goger, Gamze
    Demirci, Fatih
    Abu Mohsen, Usama
    LETTERS IN DRUG DESIGN & DISCOVERY, 2014, 11 (01) : 76 - 81
  • [49] Ligand Field Parameters of Some Transition Metal Ion Complexes of Some Substituted Hydrazones and their Antibacterial Activity
    Joshi, K. T.
    Patel, J. M.
    Pancholi, A. M.
    Shukla, D. A.
    ORIENTAL JOURNAL OF CHEMISTRY, 2011, 27 (01) : 167 - 172
  • [50] Synthesis, structural elucidation and biological activities of some novel sulfonyl hydrazones as antibacterial agents
    Senkardes, Sevil
    Kiymaci, Merve Eylul
    Kale, Kubra
    Kozanoglu, Isa Murat
    Kaskatepe, Banu
    Kucukguzel, S. Guniz
    JOURNAL OF RESEARCH IN PHARMACY, 2021, 25 (02): : 135 - 141
12345