Design and synthesis of the anticonvulsant Co 2-1068: A novel neuroactive steroid modulator of the GABA(A) receptor

被引：0

作者：

Upasani, RB ^{[1
]}

Yang, KC ^{[1
]}

Hawkinson, JE ^{[1
]}

AcostaBurruel, M ^{[1
]}

McLellan, JA ^{[1
]}

Carter, R ^{[1
]}

机构：

[1] COCENSYS INC,IRVINE,CA 92718

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1997年 / 213卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：174 / MEDI

页数：1

共 50 条

[21] Design, synthesis, and discovery of novel adenosine A2A receptor agonists.
Rieger, JM
Macdonald, TL
Linden, J
Sullivan, G
Murphree, L
Marshall, M
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U40 - U40
[22] Design, synthesis, and biological evaluation of novel adenosine A2A receptor antagonists
Silverman, LS
Caldwell, J
Greenlee, WJ
Kiselgof, EY
Matasi, J
Tuishian, D
Arik, L
Foster, C
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2548 - U2549
[23] Design, synthesis, and Estrogenic activity of a novel estrogen receptor modulator -: A hybrid structure of 17β-estradiol and vitamin E in hippocampal neurons
Zhao, Liqin
Jin, Chunyang
Mao, Zisu
Gopinathan, Madathil B.
Rehder, Kenneth
Brinton, Roberta D.
JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (18) : 4471 - 4481
[24] SAGE-324/BIIB124, an Oral Neuroactive Steroid (NAS) GABAA Receptor Positive Allosteric Modulator (PAM), in Patients with Essential Tremor: Results from the Phase 2 KINETIC Trial
Bankole, Kemi
Takahashi, Koji
Qin, Min
Colquhoun, Helen
Elble, Rodger J.
ANNALS OF NEUROLOGY, 2021, 90 : S172 - S172
[25] Synthesis and characterization of novel metabotropic glutamate receptor 2/3 (mGluR2/3) positive allosteric modulator (PAM)
Branski, Piotr
Staron, Jakub
Bugno, Ryszard
Wieronska, Joanna
Bojarski, Andrzej
Burnat, Grzegorz
Palucha-Poniewiera, Agnieszka
Pilc, Andrzej
PHARMACOLOGICAL REPORTS, 2011, 63 (02) : 577 - 577
[26] Synthesis and characterization of novel metabotropic glutamate receptor 2/3 (mGluR2/3) positive allosteric modulator (PAM)
Piotr Brański
Jakub Staroń
Ryszard Bugno
Joanna Wierońska
Andrzej Bojarski
Grzegorz Burnat
Agnieszka Pałucha-Poniewiera
Andrzej Pilc
Pharmacological Reports, 2011, 63 (2) : 577 - 577
[27] Improved Synthesis of Anxiolytic, Anticonvulsant, and Antinociceptive α2/α3-GABA(A)-ergic Receptor Subtype Selective Ligands as Promising Agents to Treat Anxiety, Epilepsy, and Neuropathic
Li, Guanguan
Golani, Lalit K.
Jahan, Rajwana
Rashid, Farjana
Cook, James M.
SYNTHESIS-STUTTGART, 2018, 50 (20): : 4124 - 4132
[28] Identification and Synthesis of Selected In Vitro Generated Metabolites of the Novel Selective Androgen Receptor Modulator (SARM) 2f
Moeller, Tristan
Wen, Hui-Chung
Naumann, Nana
Krug, Oliver
Thevis, Mario
MOLECULES, 2023, 28 (14):
[29] Synthesis of novel imidazobenzodiazepines selective for the alpha 5 beta 2 gamma 2 (Bz5) GABA(A)/benzodiazepine receptor subtype
Liu, RY
Zhang, PW
McKernan, RM
Wafford, K
Cook, JM
MEDICINAL CHEMISTRY RESEARCH, 1995, 5 (09) : 700 - 709
[30] Design, synthesis and SAR studies of novel P2X receptor antagonists
Park, Jin-Hee
Lee, Ga-Eun
Cho, Joong-Heui
Jung, Kwan-Young
Jung, Younghwan
Ko, Hyojin
Park, Chul-Seung
Kim, Yong-Chul
PURINERGIC SIGNALLING, 2014, 10 (04) : 685 - 685

← 1 2 3 4 5 →