Characterization of novel antibodies for understanding MUC16 cleavage and its pathological implications in cancer

被引:0
|
作者
Aithal, Abhijit
Junker, Wade
Kaur, Sukhwinder
Das, Srustidhar
Kshirsagar, Prakash
Rachagani, Satyanarayana
Mallya, Kavita
Jain, Maneesh
Batra, Surinder K.
机构
关键词
D O I
10.1158/1538-7445.AM2016-2978
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2978
引用
收藏
页数:4
相关论文
共 50 条
  • [41] MUC16 as a serum-based prognostic indicator of prometastatic gastric cancer
    Lee, Jieun
    Lee, Sang Wook
    Kang, So Hyun
    Seol, Donghyeok
    Yoo, Mira
    Hwang, Duyeong
    Lee, Eunju
    Park, Young Suk
    Ahn, Sang-Hoon
    Suh, Yun-Suhk
    Park, Kyoung Un
    Kwon, Nak-Jung
    Kim, Hyung-Ho
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [42] Diagnostic potential of nanoparticle aided assays for MUC16 and MUC1 glycovariants in ovarian cancer
    Jain, Shruti
    Nadeem, Nimrah
    Ulfenborg, Benjamin
    Makela, Maria
    Ruma, Shamima Afrin
    Terava, Joonas
    Huhtinen, Kaisa
    Leivo, Janne
    Kristjansdottir, Bjorg
    Pettersson, Kim
    Sundfeldt, Karin
    Gidwani, Kamlesh
    INTERNATIONAL JOURNAL OF CANCER, 2022, 151 (07) : 1175 - 1184
  • [43] MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse
    Wang, Ying
    Cheon, Dong-Joo
    Lu, Zhen
    Cunningham, Sheena L.
    Chen, Chun-Ming
    Luo, Robert Z.
    Xing, Deyin
    Orsulic, Sandra
    Bast, Robert C., Jr.
    Behringer, Richard R.
    DIFFERENTIATION, 2008, 76 (10) : 1081 - 1092
  • [44] MUC16 Mutations and Prognosis in Gastric Cancer A Little Goes a Long Way
    Smyth, Elizabeth C.
    Fitzgerald, Rebecca C.
    JAMA ONCOLOGY, 2018, 4 (12) : 1698 - 1699
  • [45] Association of MUC16 mutation with survival of immune checkpoint inhibitor in patients with cancer
    Ou, Q.
    Lin, D.
    Yu, Y.
    Li, A.
    Zhang, W.
    Chen, Y.
    Liu, R.
    Tan, Y.
    Xu, M.
    Li, L.
    Yao, H.
    ANNALS OF ONCOLOGY, 2019, 30
  • [46] Membrane proximal ectodomain cleavage of MUC16 occurs in the acidifying Golgi/post-Golgi compartments
    Das, Srustidhar
    Majhi, Prabin D.
    Al-Mugotir, Mona H.
    Rachagani, Satyanarayana
    Sorgen, Paul
    Batra, Surinder K.
    SCIENTIFIC REPORTS, 2015, 5
  • [47] Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies
    Wang, Chien-Wei
    Hanson, Eliza K.
    Minkoff, Lisa
    Whelan, Rebecca J.
    CANCER BIOMARKERS, 2023, 37 (02) : 85 - 94
  • [48] Bispecific engager immunotherapy targeting the retained portion of MUC16 (MUC16ecto) is efficacious against ovarian cancer
    Yeku, O.
    Rao, T. D.
    Purdon, T.
    Brentjens, R. J.
    Spriggs, D.
    GYNECOLOGIC ONCOLOGY, 2019, 154 : 57 - 57
  • [49] Novel mesothelin-based CAR T cells targeting MUC16 as an intravesical bladder cancer therapy
    Abrahimi, Parwiz
    Khan, Jonathan
    Brentjens, Renier
    Merghoub, Taha
    Wolchok, Jedd
    CLINICAL CANCER RESEARCH, 2024, 30 (10)
  • [50] Preclinical evaluation of radiolabeled MUC16 antibodies for PET imaging of epithelial ovarian carcinoma.
    Nemieboka, Brandon E.
    Thapi, Dharmarao
    Bitton, Ariana
    Lewis, Jason S.
    CLINICAL CANCER RESEARCH, 2016, 22