Investigation and synthesis of isoform-selective histone deacetylase inhibitors

被引:0
|
作者
O'Neill, Matthew [1 ]
Wiest, Olaf [1 ]
Helquist, Paul [1 ]
机构
[1] Univ Notre Dame, Dept Chem & Biochem, Greensboro, NC USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
511
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Isoform selective inhibition of histone deacetylase-like amidohydrolases
    Meyners, C.
    Zimmermann, M.
    Kalman, S. A.
    Meyer-Almes, F. -J.
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2015, 44 : S241 - S241
  • [42] Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors
    Senger, Johanna
    Melesina, Jelena
    Marek, Martin
    Romier, Christophe
    Oehme, Ina
    Witt, Olaf
    Sippl, Wolfgang
    Jung, Manfred
    JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (04) : 1545 - 1555
  • [43] Design, synthesis, and biological evaluation of novel histone deacetylase 6 selective inhibitors
    Zhang, Tianyi
    Zhao, Xiaoyan
    Sun, Xiangpei
    Tian, Wei
    Wang, Chongqing
    Wang, Mingping
    Zhang, Yi
    Chen, Xin
    Zheng, Canhui
    JOURNAL OF SAUDI CHEMICAL SOCIETY, 2022, 26 (03)
  • [44] MEDI 150-Design and synthesis of histone deacetylase 6 selective inhibitors
    Suzuki, Takayoshi
    Kouketsu, Akiyasu
    Itoh, Yukihiro
    Hisakawa, Shinya
    Maeda, Satoko
    Yoshida, Minoru
    Nakagawa, Hidehiko
    Miyata, Naoki
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
  • [45] Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models
    Tavares, Mauricio T.
    Shen, Sida
    Knox, Tessa
    Hadley, Melissa
    Kutil, Zsofia
    Barinka, Cyril
    Villagra, Alejandro
    Kozikowski, Alan P.
    ACS MEDICINAL CHEMISTRY LETTERS, 2017, 8 (10): : 1031 - 1036
  • [46] Peptide Arrays Identify Isoform-Selective Substrates for Profiling Endogenous Lysine Deacetylase Activity
    Gurard-Levin, Zachary A.
    Kilian, Kristopher A.
    Kim, Joohoon
    Baehr, Katinka
    Mrksich, Milan
    ACS CHEMICAL BIOLOGY, 2010, 5 (09) : 863 - 873
  • [47] Isoform-selective glucuronidation of triclosan
    Jackson, Erin N.
    Schneider, Jennifer
    Faux, Laura Rowland
    James, Margaret O.
    FASEB JOURNAL, 2013, 27
  • [48] Discovery and characterization of PI3Kbeta isoform-selective inhibitors
    Virone-Oddos, A.
    Halley, F.
    Delorme, C.
    Bonnevaux, H.
    Nicolas, J. P.
    Karlsson, A.
    Abecassis, P. Y.
    Vincent, L.
    Lengauer, C.
    EJC SUPPLEMENTS, 2010, 8 (07): : 43 - 43
  • [49] Isoform-Selective Targeting of Facilitative Glucose Transporters with Small Molecule Inhibitors
    Heitmeier, Monique
    Hresko, Richard C.
    Shanmugam, Mala
    Hruz, Paul W.
    DIABETES, 2018, 67
  • [50] Identification of potential isoform-selective histone deacetylase inhibitors for cancer therapy: a combined approach of structure-based virtual screening, ADMET prediction and molecular dynamics simulation assay
    Uba, Abdullahi Ibrahim
    Yelekci, Kemal
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2018, 36 (12): : 3231 - 3245