Developing small-molecule libraries for drug discovery

被引:4
|
作者
Gravert, DJ [1 ]
Janda, KD [1 ]
机构
[1] SCRIPPS RES INST, DEPT CHEM, LA JOLLA, CA 92037 USA
关键词
D O I
10.1016/0167-7799(96)30006-1
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:110 / 112
页数:3
相关论文
共 50 条
  • [21] Open source drug discovery: Small-molecule screening in academia
    Tolliday, Nicola
    JOURNAL OF BIOMOLECULAR SCREENING, 2008, 13 (07) : 703 - 704
  • [22] Fidelity by design: Yoctoreactor and binder trap enrichment for small-molecule DNA-encoded libraries and drug discovery
    Blakskjaer, Peter
    Heitner, Tara
    Hansen, Nils Jakob Vest
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2015, 26 : 62 - 71
  • [23] SYNTHESIS OF SMALL-MOLECULE COMBINATORIAL LIBRARIES AND THE DISCOVERY OF A POTENT ENZYME-INHIBITOR
    MURPHY, MM
    SCHULLEK, JR
    GORDON, EM
    GALLOP, MA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 143 - ORGN
  • [24] Drug Discovery Conference 2008 - Small-Molecule Drug Discovery: From Early Stage to the Clinic
    Terrett, Nicholas K.
    IDRUGS, 2008, 11 (03) : 164 - 168
  • [25] Antibody clamps pry open small-molecule drug discovery opportunities
    Mullard, Asher
    NATURE REVIEWS DRUG DISCOVERY, 2022, 21 (04) : 247 - 248
  • [26] Dynamic diversity in drug discovery: Putting small-molecule evolution to work
    Karan, C
    Miller, BL
    DRUG DISCOVERY TODAY, 2000, 5 (02) : 67 - 75
  • [27] IDENTIFYING SMALL-MOLECULE LEAD COMPOUNDS - THE SCREENING APPROACH TO DRUG DISCOVERY
    BEVAN, P
    RYDER, H
    SHAW, A
    TRENDS IN BIOTECHNOLOGY, 1995, 13 (03) : 115 - 121
  • [28] A fully integrated protein crystallization platform for small-molecule drug discovery
    Hosfield, D
    Palan, J
    Hilgers, M
    Scheibe, D
    McRee, DE
    Stevens, RC
    JOURNAL OF STRUCTURAL BIOLOGY, 2003, 142 (01) : 207 - 217
  • [29] The process of drug discovery and the Yin/Yang of small-molecule/biotech option
    Navarra, Pierluigi
    MICROCHEMICAL JOURNAL, 2018, 136 : 139 - 142
  • [30] Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review
    Zheng, Jia
    Zhang, Wei
    Li, Linfeng
    He, Yi
    Wei, Yue
    Dang, Yongjun
    Nie, Shenyou
    Guo, Zufeng
    FRONTIERS IN CHEMISTRY, 2022, 10