SYNTHESIS OF SMALL-MOLECULE COMBINATORIAL LIBRARIES AND THE DISCOVERY OF A POTENT ENZYME-INHIBITOR

被引：0
|
作者：
MURPHY, MM [1 ]
SCHULLEK, JR [1 ]
GORDON, EM [1 ]
GALLOP, MA [1 ]
机构：
[1] AFFYMAX RES INST,PALO ALTO,CA 94304
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1995年 / 209卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：143 / ORGN
相关论文
共 50 条
  • [1] Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG
    Uttamchandani, M
    Walsh, DP
    Khersonsky, SM
    Huang, X
    Yao, SQ
    Chang, YT
    JOURNAL OF COMBINATORIAL CHEMISTRY, 2004, 6 (06): : 862 - 868
  • [2] Developing small-molecule libraries for drug discovery
    Gravert, DJ
    Janda, KD
    TRENDS IN BIOTECHNOLOGY, 1996, 14 (04) : 110 - 112
  • [3] Developing small-molecule libraries for drug discovery
    Trends Biotechnol, 4 (110):
  • [4] Applications of small-molecule combinatorial chemistry to drug discovery
    Patel, DV
    Gordon, EM
    DRUG DISCOVERY TODAY, 1996, 1 (04) : 134 - 144
  • [5] Liquid-phase combinatorial synthesis: In search of small-molecule enzyme mimics
    Vandersteen, AM
    Han, H
    Janda, KD
    MOLECULAR DIVERSITY, 1996, 2 (1-2) : 89 - 96
  • [6] NEW PROMISE IN COMBINATORIAL CHEMISTRY - SYNTHESIS, CHARACTERIZATION, AND SCREENING OF SMALL-MOLECULE LIBRARIES IN SOLUTION
    CARELL, T
    WINTNER, EA
    SUTHERLAND, AJ
    REBEK, J
    DUNAYEVSKIY, YM
    VOUROS, P
    CHEMISTRY & BIOLOGY, 1995, 2 (03): : 171 - 183
  • [7] Discovery of a Small-Molecule Inhibitor of β-1,6-Glucan Synthesis
    Kitamura, Akihiro
    Someya, Kazuhiko
    Hata, Masato
    Nakajima, Ryohei
    Takemura, Makoto
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (02) : 670 - 677
  • [8] Discovery of BT-114143, a Novel and Potent Small-Molecule Plasminogen Inhibitor for Hyperfibrinolysis
    Tang, Jun
    Ji, Sen
    Hu, Xiao
    Wang, Yan
    Qi, Jun
    Wang, Xiao
    Wang, Hao
    Li, Jianzong
    Li, Zhiqiang
    Li, Min
    Zeng, Shaomei
    Yuan, Xiong
    Zhang, Xiaodong
    BLOOD, 2023, 142
  • [9] ANALOGOUS ORGANIC-SYNTHESIS OF SMALL-COMPOUND LIBRARIES - VALIDATION OF COMBINATORIAL CHEMISTRY IN SMALL-MOLECULE SYNTHESIS
    CHEN, CX
    RANDALL, LAA
    MILLER, RB
    JONES, AD
    KURTH, MJ
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (06) : 2661 - 2662
  • [10] Discovery of potent small-molecule inhibitors of lipoprotein(a) formation
    Diaz, Nuria
    Perez, Carlos
    Escribano, Ana Maria
    Sanz, Gema
    Priego, Julian
    Lafuente, Celia
    Barberis, Mario
    Calle, Luis
    Espinosa, Juan Felix
    Priest, Birgit T.
    Zhang, Hong Y.
    Nosie, Amanda K.
    Haas, Joseph V.
    Cannady, Ellen
    Borel, Anthony
    Schultze, Albert E.
    Sauder, J. Michael
    Hendle, Jorg
    Weichert, Ken
    Nicholls, Stephen J.
    Michael, Laura F.
    NATURE, 2024, 629 (8013) : 945 - 950
12345