Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits

被引：8
|
作者：
Kayan, Autchara [1 ,2 ]
Uddin, Muhammad Jasim [1 ,3 ]
Kocamis, Hakan [4 ]
Tesfaye, Dawit [1 ]
Looft, Christian [1 ]
Tholen, Ernst [1 ]
Schellander, Karl [1 ]
Cinar, Mehmet Ulas [1 ]
机构：
[1] Univ Bonn, Inst Anim Sci, Anim Breeding & Husb Grp, D-53115 Bonn, Germany
[2] Kasetsart Univ, Fac Agr, Dapartment Anim Sci, Bangkok 10900, Thailand
[3] Bangladesh Agr Univ, Fac Vet Sci, Dept Med, Mymensingh 2202, Bangladesh
[4] Kirikkale Univ, Fac Vet, Dept Histol & Embryol, TR-71450 Kirikkale, Turkey
来源：
MEAT SCIENCE | 2013年 / 94卷 / 04期
关键词：
HNF1A; Single nucleotide polymorphism; mRNA and protein expression; Methylation; Meat quality; Pig; INTRAMUSCULAR FAT-CONTENT; ACID-COMPOSITION; DNA METHYLATION; QTL; IDENTIFICATION; HEPATOCYTE-NUCLEAR-FACTOR-1-ALPHA; POLYMORPHISMS; ACTIVATION; FATNESS; TARGET;
D O I：
10.1016/j.meatsci.2013.04.015
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The aim of this study was to investigate the association and expression of HNF1A gene as a candidate gene for meat and carcass quality traits in pigs. Statistical analysis revealed that the g.8260 A>G polymorphism significantly associated with pH 24(H), meat percentage and muscle area in the F-2 Duroc x Pietrain (DuPi, n = 313) and with pH 24(L), fat area and backfat thickness in the Pietrain (Pi, n = 110) population. HNF1A mRNA and protein expressions were higher (p < 0.05) in animals with the low post-mortem muscle pH 24(L). The promoter methylation profiling suggested that methylation was not involved on HNF1A expression regulation (p > 0.05) in animal with divergent muscle pH. In conclusion, polymorphism in porcine HNF1A gene could be used as a candidate marker to improve the meat and carcass quality traits, with the consideration of breed-specific effect. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：474 / 479
页数：6
相关论文
共 50 条
  • [21] Molecular Characterization, Expression Profile, and Association Study with Meat Quality Traits of Porcine PFKM Gene
    Jun Wang
    Liang Qin
    Yanping Feng
    Rong Zheng
    Changyan Deng
    Yuanzhu Xiong
    Bo Zuo
    Applied Biochemistry and Biotechnology, 2014, 173 : 1640 - 1651
  • [22] Molecular characterization, expression and association analysis of the porcine CMYA4 gene with carcass traits
    Xu, X. L.
    Li, K.
    Peng, Z. Z.
    Zhao, S. H.
    Yu, M.
    Fan, B.
    Zhu, M. J.
    Xu, S. P.
    Du, Y. Q.
    Liu, B.
    JOURNAL OF ANIMAL BREEDING AND GENETICS, 2008, 125 (04) : 234 - 239
  • [23] Variation in the HSL Gene and Its Association with Carcass and Meat Quality Traits in Yak
    Wang, Xiangyan
    Qi, Youpeng
    Zhu, Chune
    Zhou, Ruifeng
    Ruo, Zhoume
    Zhao, Zhidong
    Liu, Xiu
    Li, Shaobin
    Zhao, Fangfang
    Wang, Jiqing
    Hu, Jiang
    Shi, Bingang
    ANIMALS, 2023, 13 (23):
  • [24] Association of thyroglobulin gene variants with carcass and meat quality traits in beef cattle
    Hou, Guan-Yu
    Yuan, Zheng-Rong
    Zhou, Han-Lin
    Zhang, Lu-Pei
    Li, Jun-Ya
    Gao, Xue
    Wang, Dong-Jing
    Gao, Hui-Jiang
    Xu, Shang-Zhong
    MOLECULAR BIOLOGY REPORTS, 2011, 38 (07) : 4705 - 4708
  • [25] Association of LXRA gene variants with carcass and meat quality traits in beef cattle
    Gan, Qianfu
    Zhang, Lupei
    Xu, Shangzhong
    Li, Hengde
    Li, Junya
    Gao, Xue
    Ren, Hongyan
    Chen, Jinbao
    AFRICAN JOURNAL OF BIOTECHNOLOGY, 2008, 7 (20): : 3546 - 3549
  • [26] Association of thyroglobulin gene variants with carcass and meat quality traits in beef cattle
    Guan-Yu Hou
    Zheng-Rong Yuan
    Han-Lin Zhou
    Lu-Pei Zhang
    Jun-Ya Li
    Xue Gao
    Dong-Jing Wang
    Hui-Jiang Gao
    Shang-Zhong Xu
    Molecular Biology Reports, 2011, 38 : 4705 - 4708
  • [27] Polymorphism and expression of the porcine Tenascin C gene associated with meat and carcass quality
    Kayan, A.
    Cinar, M. U.
    Uddin, M. J.
    Phatsara, C.
    Wimmers, K.
    Ponsuksili, S.
    Tesfaye, D.
    Looft, C.
    Juengst, H.
    Tholen, E.
    Schellander, K.
    MEAT SCIENCE, 2011, 89 (01) : 76 - 83
  • [28] Sequence and haplotypes of ankyrin 1 gene (ANK1) and their association with carcass and meat quality traits in yak
    Hu, Jiang
    Gao, Xiaoli
    Shi, Bingang
    Chen, Haiqing
    Zhao, Zhidong
    Wang, Jiqing
    Liu, Xiu
    Li, Shaobin
    Luo, Yuzhu
    MAMMALIAN GENOME, 2021, 32 (02) : 104 - 114
  • [29] Sequence and haplotypes of ankyrin 1 gene (ANK1) and their association with carcass and meat quality traits in yak
    Jiang Hu
    Xiaoli Gao
    Bingang Shi
    Haiqing Chen
    Zhidong Zhao
    Jiqing Wang
    Xiu Liu
    Shaobin Li
    Yuzhu Luo
    Mammalian Genome, 2021, 32 : 104 - 114
  • [30] Molecular characterization, expression pattern, and association analysis with carcass traits of the porcine SHIP2 gene
    Qi Xiong
    Jin Chai
    Changyan Deng
    Siwen Jiang
    Xiaofeng Li
    Xiaojun Suo
    Nian Zhang
    Qianping Yang
    Yang Liu
    Rong Zheng
    Mingxin Chen
    Molecular and Cellular Biochemistry, 2012, 360 : 225 - 233
12345