Olfactory Loss in Parkinson's Disease

被引:97
|
作者
Haehner, Antje [1 ,2 ]
Hummel, Thomas [1 ]
Reichmann, Heinz [2 ]
机构
[1] Tech Univ Dresden, Sch Med, Dept Otorhinolaryngol, D-01307 Dresden, Germany
[2] Tech Univ Dresden, Sch Med, Dept Neurol, D-01307 Dresden, Germany
关键词
ODOR IDENTIFICATION; DE-NOVO; DYSFUNCTION; HYPOSMIA; IMPAIRMENT; BULB; ASSOCIATION; PERFORMANCE; PREDICTORS; SYMPTOMS;
D O I
10.4061/2011/450939
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Impairment of olfaction is a characteristic and early feature of Parkinson's disease. Recent data indicate that >95% of patients with Parkinson's disease present with significant olfactory loss. Deficits in the sense of smell may precede clinical motor symptoms by years and can be used to assess the risk for developing Parkinson's disease in otherwise asymptomatic individuals. This paper summarizes the available information about olfactory function in Parkinson's disease, indicating the advantageous use of olfactory probes in early and differential diagnosis.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Olfactory dysfunction and Parkinson's disease progression
    Hower, Renee E.
    Rick, Jacqueline H.
    Balderston, Catherine C.
    Weintraub, Daniel
    Siderowf, Andrew
    Stern, Matthew
    Moberg, Paul
    Duda, John
    NEUROLOGY, 2008, 70 (11) : A397 - A398
  • [22] Olfactory fMRI in patients with Parkinson's disease
    Hummel, Thomas
    Fliessbach, Klaus
    Abele, Michael
    Okulla, Thorsten
    Reden, Jens
    Reichmann, Heinz
    Wuellner, Ullrich
    Haehner, Antje
    FRONTIERS IN INTEGRATIVE NEUROSCIENCE, 2010, 4
  • [23] Olfactory and visual hallucinations in Parkinson's disease
    Tousi, B
    Frankel, M
    PARKINSONISM & RELATED DISORDERS, 2004, 10 (04) : 253 - 254
  • [24] Olfactory Training and Cognition in Parkinson's Disease
    Haehner, Antje
    Rauber, Claudio
    Wegener, Birte-Antina
    Croy, Ilona
    Hummel, Thomas
    CHEMICAL SENSES, 2016, 41 (07) : E78 - E78
  • [25] Olfactory Dysfunction and Dementia in Parkinson's Disease
    Takeda, Atsushi
    Baba, Toru
    Kikuchi, Akio
    Hasegawa, Takafumi
    Sugeno, Naoto
    Konno, Masatoshi
    Miura, Emiko
    Mori, Etsuro
    JOURNAL OF PARKINSONS DISEASE, 2014, 4 (02) : 181 - 187
  • [26] Retronasal Olfactory Function in Parkinson's Disease
    Landis, Basile N.
    Van, Helene Cao
    Guinand, Nils
    Horvath, Judit
    Haehner, Antje
    Savva, Elena
    Hugentobler, Marianne
    Lacroix, Jean-Silvain
    Burkhard, Pierre R.
    LARYNGOSCOPE, 2009, 119 (11): : 2280 - 2283
  • [27] OLFACTORY HALLUCINATIONS IN IDIOPATHIC PARKINSON'S DISEASE
    McAuley, J.
    Gregory, S.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2012, 83 : A13 - A13
  • [28] Is Parkinson's disease a primary olfactory disorder?
    Hawkes, CH
    Shephard, BC
    Daniel, SE
    QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS, 1999, 92 (08): : 473 - 480
  • [29] Olfactory dysfunction: A symptom of Parkinson's disease?
    Radil, T
    Roth, J
    Ruzicka, E
    Tichy, J
    Wysocki, CJ
    CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, 1995, 58 (06): : 286 - 289
  • [30] Olfactory Training in Patients with Parkinson's Disease
    Haehner, Antje
    Tosch, Clara
    Wolz, Martin
    Klingelhoefer, Lisa
    Fauser, Mareike
    Storch, Alexander
    Reichmann, Heinz
    Hummel, Thomas
    PLOS ONE, 2013, 8 (04):