Nanofabricated upconversion nanoparticles for photodynamic therapy

被引：115

作者：

Ungun, Baris ^{[1
]}

Prud'homme, Robert K. ^{[2
]}

Budijono, Stephanie J. ^{[1
]}

Shan, Jingning ^{[2
]}

Lim, Shuang Fang ^{[2
,3
]}

Ju, Yiguang ^{[2
]}

Austin, Robert ^{[3
]}

机构：

[1] Princeton Univ, Dept Chem Engn, Princeton, NJ 08544 USA

[2] Princeton Univ, Dept Mech & Aerosp Engn, Princeton, NJ 08544 USA

[3] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

来源：

OPTICS EXPRESS | 2009年 / 17卷 / 01期

基金：

美国国家科学基金会;

关键词：

ORGANIC ACTIVES; SINGLET OXYGEN; ACID;

D O I：

10.1364/OE.17.000080

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present a novel process for the production of three-layer Composite Nanoparticles (CNPs) in the size range 100-300 nm with an up-converting phosphor interior, a coating of porphyrin photosensitizer, and a biocompatible PEG outer layer to prevent clearance by the reticuloendothelial system. We show that these CNPs produce millimolar amounts of singlet oxygen at NIR intensities far less than other two-photon techniques. (C) 2008 Optical Society of America

引用

页码：80 / 86

页数：7

共 50 条

[41] Upconversion Composite Nanoparticles for Tumor Hypoxia Modulation and Enhanced Near-Infrared-Triggered Photodynamic Therapy
Gu, Tongxu
Cheng, Liang
Gong, Fei
Xu, Jun
Li, Xiang
Han, Gaorong
Liu, Zhuang
ACS APPLIED MATERIALS & INTERFACES, 2018, 10 (18) : 15494 - 15503
[42] Theranostic micelles based on upconversion nanoparticles for dual-modality imaging and photodynamic therapy in hepatocellular carcinoma
Han, Yong
An, Yanli
Jia, Gang
Wang, Xihui
He, Chen
Ding, Yinan
Tang, Qiusha
NANOSCALE, 2018, 10 (14) : 6511 - 6523
[43] Degradable Calcium Phosphate-Coated Upconversion Nanoparticles for Highly Efficient Chemo-Photodynamic Therapy
Liu, Shikai
Li, Wenting
Dong, Shuming
Gai, Shili
Dong, Yushan
Yang, Dan
Dai, Yunlu
He, Fei
Yang, Piaoping
ACS APPLIED MATERIALS & INTERFACES, 2019, 11 (51) : 47659 - 47670
[44] Conquering multidrug resistant lung cancer by upconversion nanoparticles-mediated photodynamic therapy and gene silencing
Kalluru, Poliraju
Shanmugam, Munusamy
Vankayala, Raviraj
Chiang, Chi-Shiun
Hwang, Kuo Chu
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2022, 69 (08) : 1305 - 1317
[45] Amphiphilic chitosan modified upconversion nanoparticles for in vivo photodynamic therapy induced by near-infrared light
Cui, Sisi
Chen, Haiyan
Zhu, Hongyan
Tian, Junmei
Chi, Xuemei
Qian, Zhiyu
Achilefu, Samuel
Gu, Yueqing
JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (11) : 4861 - 4873
[46] Design, synthesis and photocytotoxicity of upconversion nanoparticles: Potential applications for near-infrared photodynamic and photothermal therapy
Hu, Yang
Honek, John F.
Wilson, Brian C.
Lu, Qing-Bin
JOURNAL OF BIOPHOTONICS, 2019, 12 (11)
[47] Leveraging Spectral Matching between Photosensitizers and Upconversion Nanoparticles for 808 nm-Activated Photodynamic Therapy
He, Sha
Johnson, Noah J. J.
Viet Anh Nguyen Huu
Huang, Yuran
Almutairi, Adah
CHEMISTRY OF MATERIALS, 2018, 30 (12) : 3991 - 4000
[48] Hierarchical nanoparticles in photodynamic therapy
Eldabagh, Noor
Foley, Jonathan
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[49] Inorganic Nanoparticles for Photodynamic Therapy
Colombeau, L.
Acherar, S.
Baros, F.
Arnoux, P.
Gazzali, A. Mohd
Zaghdoudi, K.
Toussaint, M.
Vanderesse, R.
Frochot, C.
LIGHT-RESPONSIVE NANOSTRUCTURED SYSTEMS FOR APPLICATIONS IN NANOMEDICINE, 2016, 370 : 113 - 134
[50] Near infrared light activated upconversion nanoparticles (UCNP) based photodynamic therapy of prostate cancers: An in vitro study
Guleryuz, Burcu
Unal, Ugur
Gulsoy, Murat
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2021, 36

← 1 2 3 4 5 →