Cardiac mechanosensitivity and stretch-activated ion channels

被引：21
|
作者：
Bett, GCL
Sachs, F
机构：
[1] Department of Biophysical Sciences, State University of New York, Buffalo
来源：
TRENDS IN CARDIOVASCULAR MEDICINE | 1997年 / 7卷 / 01期
关键词：
D O I：
10.1016/S1050-1738(96)00119-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Mechanosensitivity is a ubiquitous property of cells, and mechanosensitive ion channels (MSCs) are hypothesized to be the transducers. In the heart MSCs are likely to account for changes in beating rate as a function of filling and for initiating stretch-induced arrhythmias (for example, following a myocardial infarction). Pharmacological agents that affect MSCs may provide a new class of antiarrhythmic drugs. (C) 1997, Elsevier Science Inc.
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页码：4 / 8
页数：5
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