Synthesis and antioxidant activity of a novel class of fluorescein-based β-C-glycosides

被引：11
|
作者：
Rajasekar, Mani [1 ]
Das, Thangamuthu Mohan [1 ,2 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
[2] CUTN, Sch Basic & Appl Sci, Dept Chem, Thiruvarur 610004, India
来源：
CARBOHYDRATE RESEARCH | 2013年 / 379卷
关键词：
Fluorescein derivatives; beta-C-glycosides; Aldol condensation; Antioxidant activity; CONDENSATION; ANALOG;
D O I：
10.1016/j.carres.2013.06.016
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A series of fluorescein-based beta-C-glycosyl ketones were synthesized through aldol condensation of beta-C-glycosyl ketones with fluorescein monoaldehyde under ambient reaction conditions in good yields. Formation of the expected product has been confirmed through different spectral techniques. Fluorescein-based beta-C-glycosides show moderate anti-oxidant activities with maximum inhibitory activity of 60%. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：38 / 42
页数：5
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