Interplay Between Calcium and AMPK Signaling in Human Cytomegalovirus Infection

被引：18
|
作者：
Dunn, Diana M. [1 ]
Munger, Joshua [1 ]
机构：
[1] Univ Rochester, Sch Med & Dent, Dept Biochem & Biophys, Rochester, NY 14627 USA
来源：
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2020年 / 10卷
关键词：
cytomegalovirus; HCMV; calcium signaling; AMPK; cancer; oncomodulation; CA2+/CALMODULIN-DEPENDENT PROTEIN-KINASE; MUSCLE PHOSPHORYLASE-KINASE; LIGHT-CHAIN KINASE; LOCALIZED INHIBITOR; MYOGENIN EXPRESSION; MOLECULAR-CLONING; CANCER-PATIENTS; CALMODULIN; ACTIVATION; PROMOTES;
D O I：
10.3389/fcimb.2020.00384
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Calcium signaling and the AMP-activated protein kinase (AMPK) signaling networks broadly regulate numerous aspects of cell biology. Human Cytomegalovirus (HCMV) infection has been found to actively manipulate the calcium-AMPK signaling axis to support infection. Many HCMV genes have been linked to modulating calcium signaling, and HCMV infection has been found to be reliant on calcium signaling and AMPK activation. Here, we focus on the cell biology of calcium and AMPK signaling and what is currently known about how HCMV modulates these pathways to support HCMV infection and potentially contribute to oncomodulation.
引用
收藏
页数：14
相关论文
共 50 条
  • [31] Pneumonitis in human cytomegalovirus infection
    Langhoff E.
    Siegel R.E.
    Current Infectious Disease Reports, 2006, 8 (3) : 222 - 230
  • [32] HUMAN CYTOMEGALOVIRUS - BIOLOGICAL AND INFECTION
    GEGINAT, G
    HAMPL, W
    MERTENS, T
    MEDIZINISCHE KLINIK, 1992, 87 : 3 - 10
  • [33] IMMUNOBIOLOGY OF INFECTION WITH HUMAN CYTOMEGALOVIRUS
    KIRCHNER, H
    ADVANCES IN CANCER RESEARCH, 1983, 40 : 31 - 105
  • [34] Human cytomegalovirus infection and atherothrombosis
    Popovic, Milan
    Smiljanic, Katarina
    Dobutovic, Branislava
    Syrovets, Tatiana
    Simmet, Thomas
    Isenovic, Esma R.
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2012, 33 (02) : 160 - 172
  • [35] A Peptide Link Between Human Cytomegalovirus Infection, Neuronal Migration, and Psychosis
    Lucchese, Guglielmo
    Floeel, Agnes
    Stahl, Benjamin
    FRONTIERS IN PSYCHIATRY, 2020, 11
  • [36] No evidence of association between human cytomegalovirus infection and papillary thyroid cancer
    Tung-Sun Huang
    Jie-Jen Lee
    Shih-Ping Cheng
    World Journal of Surgical Oncology, 12
  • [37] No evidence of association between human cytomegalovirus infection and papillary thyroid cancer
    Huang, Tung-Sun
    Lee, Jie-Jen
    Cheng, Shih-Ping
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2014, 12
  • [38] Intracellular signaling by the chemokine receptor US28 during human cytomegalovirus infection
    Billstrom, MA
    Johnson, GL
    Avdi, NJ
    Worthen, GS
    JOURNAL OF VIROLOGY, 1998, 72 (07) : 5535 - 5544
  • [39] The interplay between MAMP and SA signaling
    Tsuda, Kenichi
    Glazebrook, Jane
    Katagiri, Fumiaki
    PLANT SIGNALING & BEHAVIOR, 2008, 3 (06) : 359 - 361
  • [40] Interplay between TGF-β and WNT signaling pathways in human cardiac fibroblasts
    Dzialo, E.
    Rudnik, M.
    Siedlar, M.
    Kania, G.
    Blyszczuk, P.
    FEBS OPEN BIO, 2019, 9 : 17 - 17
12345