IgE-mediated anaphylactic reaction to purified and recombinant factor VIII in a patient with severe haemophilia A

被引：16

作者：

Kadar, J. G.

Schuster, J.

Hunzelmann, N.

机构：

[1] Klin & Poliklin Dermatol & Vererol, D-50931 Cologne, Germany

[2] Univ Cologne, Outpatient Clin, Cologne, Germany

[3] Univ Cologne, Lab Transfus Med, Cologne, Germany

[4] Univ Cologne, Dept Dermatol, Cologne, Germany

来源：

HAEMOPHILIA | 2007年 / 13卷 / 01期

关键词：

allergy; bleeding disorder; IgE-mediated reaction; inhibitors; recombinant;

D O I：

10.1111/j.1365-2516.2006.01339.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a 51-year-old patient with severe haemophilia A developing a severe life-threatening anaphylactic reaction to recombinant factor VIII (rFVIII). Anaphylactic reactions are a rare but well-known side effect of FVIII products. The nature of these reactions could not be clarified as previous studies failed to demonstrate a specific IgE response. Here, we could prove a grade 3 anaphlyactic reaction as an IgE-mediated response to rFVIII for the first time by Western blotting.

引用

页码：104 / 105

页数：2

共 50 条

[41] Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation
Lu, Yue
Yang, Ju Hye
Li, Xian
Hwangbo, Kyoung
Hwang, Seung-Lark
Taketomi, Yoshitaka
Murakami, Makoto
Chang, Young-Chae
Kim, Cheorl-Ho
Son, Jong-Keun
Chang, Hyeun Wook
BIOCHEMICAL PHARMACOLOGY, 2011, 82 (11) : 1700 - 1708
[42] IgE-mediated anaphylactic reactions to neuromuscular blocking agents: Can they be prevented?
E. Florvaag
S. G. O. Johansson
Current Allergy and Asthma Reports, 2008, 8 : 375 - 376
[43] IgE-mediated anaphylactic reactions to neuromuscular blocking agents: Can they be prevented?
Florvaag, E.
Johansson, S. G. O.
CURRENT ALLERGY AND ASTHMA REPORTS, 2008, 8 (05) : 375 - 376
[44] Allergic reaction mediated by IgE in hemophilia A patient using plasma-derived factor VIII concentrate is not acting against factor VIII protein
Montalvao, Silmara
Tucunduva, Aline
Sambo, Andrea
Medina, Samuel
Ozelo, Margareth
HAEMOPHILIA, 2014, 20 : 51 - 51
[45] IgE-mediated allergy to recombinant human insulin in a diabetic
Baur, X
Bossert, J
Koops, F
ALLERGY, 2003, 58 (07) : 676 - 678
[46] Role of selectins on IgE-mediated skin reaction
Wada, Y
Kuzuhara, A
Hanamura, M
Kida, R
Yoshinaka, T
Saito, T
BRITISH JOURNAL OF PHARMACOLOGY, 2000, 131 (08) : 1531 - 1536
[47] POSSIBLE ROLE OF IGE-MEDIATED REACTION IN IMMUNITY
STEINBERG, P
ISHIZAKA, K
NORMAN, PS
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1974, 54 (06) : 359 - 366
[48] Dieckol, a phlorotannin of Ecklonia cava, suppresses IgE-mediated mast cell activation and passive cutaneous anaphylactic reaction
Ahn, Ginnae
Amagai, Yosuke
Matsuda, Akira
Kang, Sung-Myung
Lee, WonWoo
Jung, Kyungsook
Oida, Kumiko
Jang, Hyosun
Ishizaka, Saori
Matsuda, Kenshiro
Jeon, You-Jin
Jee, Youngheun
Matsuda, Hiroshi
Tanaka, Akane
EXPERIMENTAL DERMATOLOGY, 2015, 24 (12) : 968 - 970
[49] PERIOPERATIVE MANAGEMENT OF PATIENTS WITH SEVERE HAEMOPHILIA A WITH RECOMBINANT FACTOR VIII FC FUSION PROTEIN (RFVIIIFC)
Bocchinfuso, S.
O'Donovan, M.
Singleton, E.
Benson, J.
Byrne, M.
Ryan, K.
O'Donnell, J. S.
O'Connell, N. M.
HAEMOPHILIA, 2021, 27 : 105 - 106
[50] Severe anaphylactic reaction to glatiramer acetate with specific IgE
Rauschka, H
Farina, C
Sator, P
Gudek, S
Breier, F
Schmidbauer, M
NEUROLOGY, 2005, 64 (08) : 1481 - 1482

← 1 2 3 4 5 →