Lab-on-CMOS: A Multi-modal CMOS Sensor Platform towards Personalized DNA Sequencing

被引：0

作者：

Jiang, Yu ^{[1
]}

Liu, Xu ^{[1
]}

Huang, Xiwei ^{[2
]}

Shang, Yang ^{[1
]}

Yan, Mei ^{[1
]}

Yu, Hao ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore

[2] Hangzhou Dianzi Univ, Key Lab RF Circuits & Syst, Minist Educ, Hangzhou 310018, Zhejiang, Peoples R China

来源：

2016 IEEE INTERNATIONAL SYMPOSIUM ON CIRCUITS AND SYSTEMS (ISCAS) | 2016年

关键词：

personalized DNA sequencing; label-free sensors; ISFET; metamaterial sensor; multi-modal;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Precision medicine requires scalable bio-instrument for a personalized DNA sequencing, which can be label-free, cost-efficient, and high-throughput. This paper mainly presents three kinds of CMOS-based label-free sensors, including: i) a high-sensitivity ion-sensitive field-effect transistor (ISFET) sensor with pH-to-time-to-voltage conversion (pH-TVC); ii) a dual-mode sensor with image and chemical modes for high accuracy; and iii) a THz metamaterial sensor with electrical resonance detection. The developed CMOS multi-modal sensor platform can show a scaled solution for future personalized DNA sequencing.

引用

页码：2266 / 2269

页数：4

共 45 条

[31] Intracellular cardiomyocytes potential recording by planar electrode array and fibroblasts co-culturing on multi-modal CMOS chip
Park, Jong Seok
Grijalva, Sandra I.
Jung, Doohwan
Li, Sensen
Junek, Gregory V.
Chi, Taiyun
Cho, Hee Cheol
Wang, Hua
BIOSENSORS & BIOELECTRONICS, 2019, 144
[32] A Personalized Course Resource Recommendation Method Based on Deep Learning in an Online Multi-Modal Multimedia Education Cloud Platform
Zhang, Ruiping
INTERNATIONAL JOURNAL OF INFORMATION TECHNOLOGIES AND SYSTEMS APPROACH, 2023, 16 (02)
[33] Multi-modal sensor fusion towards three-dimensional airborne sonar imaging in hydrodynamic conditions
Aidan Fitzpatrick
Roshan P. Mathews
Ajay Singhvi
Amin Arbabian
Communications Engineering, 2 (1):
[34] A digital CMOS-based 24 x 16 sensor array platform for fully automatic electrochemical DNA detection
Kruppa, Philipp
Frey, Alexander
Kuehne, Ingo
Schienle, Meinrad
Persike, Norbert
Kratzmueller, Thomas
Hartwich, Gerhard
Schmitt-Landsiedel, Doris
BIOSENSORS & BIOELECTRONICS, 2010, 26 (04): : 1414 - 1419
[35] Highlights lecture EANM 2016: "Embracing molecular imaging and multi-modal imaging: a smart move for nuclear medicine towards personalized medicine"
Aboagye, Eric O.
Kraeber-Bodere, Francoise
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 (09) : 1559 - 1574
[36] Highlights lecture EANM 2016: “Embracing molecular imaging and multi-modal imaging: a smart move for nuclear medicine towards personalized medicine”
Eric O. Aboagye
Françoise Kraeber-Bodéré
European Journal of Nuclear Medicine and Molecular Imaging, 2017, 44 : 1559 - 1574
[37] Personalized FedM2former: An Innovative Approach Towards Federated Multi-Modal 3D Object Detection for Autonomous Driving
Zhao, Liang
Li, Xuan
Jia, Xin
Fu, Lulu
PROCESSES, 2025, 13 (02)
[38] CMOS-Based Electrokinetic Microfluidics With Multi-Modal Cellular and Bio-Molecular Sensing for End-to-End Point-of-Care System
Zhu, Chengjie
Maldonado, Jesus
Sengupta, Kaushik
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2021, 15 (06) : 1250 - 1267
[39] A CMOS 21 952-Pixel Multi-Modal Cell-Based Biosensor With Four-Point Impedance Sensing for Holistic Cellular Characterization
Jung, Doohwan
Junek, Gregory, V
Park, Jong Seok
Kumashi, Sagar R.
Wang, Adam
Li, Sensen
Grijalva, Sandra Ivonne
Fernandez, Natasha
Cho, Hee Cheol
Wang, Hua
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 2021, 56 (08) : 2438 - 2451
[40] Analysis of population heterogeneity in CHO cells by genome-wide DNA methylation analysis and by multi-modal single-cell sequencing
Boehl, Elias
Raddatz, Guenter
Roy, Suki
Huang, Lingzhi
Sandhu, Jasrene Kaur
Igwe, Emeka Ignatius
Rodriguez-Paredes, Manuel
Boehl, Florian
Lyko, Frank
JOURNAL OF BIOTECHNOLOGY, 2024, 396 : 72 - 79

← 1 2 3 4 5 →