Lab-on-CMOS: A Multi-modal CMOS Sensor Platform towards Personalized DNA Sequencing

被引：0

作者：

Jiang, Yu ^{[1
]}

Liu, Xu ^{[1
]}

Huang, Xiwei ^{[2
]}

Shang, Yang ^{[1
]}

Yan, Mei ^{[1
]}

Yu, Hao ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore

[2] Hangzhou Dianzi Univ, Key Lab RF Circuits & Syst, Minist Educ, Hangzhou 310018, Zhejiang, Peoples R China

来源：

2016 IEEE INTERNATIONAL SYMPOSIUM ON CIRCUITS AND SYSTEMS (ISCAS) | 2016年

关键词：

personalized DNA sequencing; label-free sensors; ISFET; metamaterial sensor; multi-modal;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Precision medicine requires scalable bio-instrument for a personalized DNA sequencing, which can be label-free, cost-efficient, and high-throughput. This paper mainly presents three kinds of CMOS-based label-free sensors, including: i) a high-sensitivity ion-sensitive field-effect transistor (ISFET) sensor with pH-to-time-to-voltage conversion (pH-TVC); ii) a dual-mode sensor with image and chemical modes for high accuracy; and iii) a THz metamaterial sensor with electrical resonance detection. The developed CMOS multi-modal sensor platform can show a scaled solution for future personalized DNA sequencing.

引用

页码：2266 / 2269

页数：4

共 45 条

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