Lab-on-CMOS: A Multi-modal CMOS Sensor Platform towards Personalized DNA Sequencing

被引：0
|
作者：
Jiang, Yu [1 ]
Liu, Xu [1 ]
Huang, Xiwei [2 ]
Shang, Yang [1 ]
Yan, Mei [1 ]
Yu, Hao [1 ]
机构：
[1] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore
[2] Hangzhou Dianzi Univ, Key Lab RF Circuits & Syst, Minist Educ, Hangzhou 310018, Zhejiang, Peoples R China
来源：
2016 IEEE INTERNATIONAL SYMPOSIUM ON CIRCUITS AND SYSTEMS (ISCAS) | 2016年
关键词：
personalized DNA sequencing; label-free sensors; ISFET; metamaterial sensor; multi-modal;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Precision medicine requires scalable bio-instrument for a personalized DNA sequencing, which can be label-free, cost-efficient, and high-throughput. This paper mainly presents three kinds of CMOS-based label-free sensors, including: i) a high-sensitivity ion-sensitive field-effect transistor (ISFET) sensor with pH-to-time-to-voltage conversion (pH-TVC); ii) a dual-mode sensor with image and chemical modes for high accuracy; and iii) a THz metamaterial sensor with electrical resonance detection. The developed CMOS multi-modal sensor platform can show a scaled solution for future personalized DNA sequencing.
引用
收藏
页码：2266 / 2269
页数：4
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