Synthesis and characterization of novel 1,2,3-triazole-linked theophylline and coumarin s-triazines

被引:0
|
作者
Joshi, Penny [1 ,2 ]
Tripathi, Mohit [1 ]
Rawat, Diwan S. [1 ]
机构
[1] Univ Delhi, Dept Chem, Delhi 110007, India
[2] Kumaun Univ, Dept Chem, Naini Tal 263001, India
关键词
s-Triazine; dendrimer; triazole; theophylline; coumarin; VITRO ANTIMALARIAL ACTIVITY; IMPROVED IN-VITRO; ANTIBACTERIAL ACTIVITY; DRUG-DELIVERY; DERIVATIVES; HYBRIDS; CYTOTOXICITY; DENDRIMERS; ANALOGS; DESIGN;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of novel s-triazine-1,2,3-triazole-theophylline and s-triazine-1,2,3-triazole-coumarin generation-0 dendrimers has been synthesized and characterized by FT-IR, H-1 and C-13 NMR, and mass-spectral methods. Some 'selected compounds have been evaluated for antibacterial and antifungal activity against a variety of strains and for anti-cancer activity against 60 human cancer cell lines.
引用
收藏
页码:311 / 318
页数:8
相关论文
共 50 条
  • [21] SYNTHESIS AND CHARACTERIZATION OF THEOPHYLLINE-TRIAZOLE AND THEOPHYLLINE-TRIAZOLE-COUMARIN BASED MOLECULAR HYBRIDS
    Joshi, Penny
    Rawat, Diwan S.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2015, 24 (04) : 411 - 418
  • [22] Microwave-Assisted Synthesis, Molecular Docking, and Insecticidal Activity of 1,2,3-Triazole-Linked Chromone Derivatives
    Manasa, S. K.
    Sadanandam, K.
    Mallavarapu, B. D.
    Shree, A. J.
    Sarasija, M.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2024, 94 (01) : 161 - 169
  • [23] Synthesis and Characterization of a New Coumarin-1,2,3-Triazole Diad
    Li, Hong-qi
    Tian, Xiu-juan
    Chen, Zhen
    Xiao, Ding
    Fang, Ning
    Lv, Yan-xiang
    Gu, Liang
    MATERIALS, MACHINES AND DEVELOPMENT OF TECHNOLOGIES FOR INDUSTRIAL PRODUCTION, 2014, 618 : 170 - 174
  • [24] SYNTHESIS AND CHARACTERIZATION OF SOME NEW 1,2,4-TRIAZINES CONTAINING 1,2,3-TRIAZOLE
    Wang, Yan-Fei
    Dong, Hong-ru
    Li, Rong-Shan
    Dong, Heng-Shan
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2012, 22 (01) : 81 - 84
  • [25] Design, synthesis, characterization, and in vitro antimicrobial action of novel trisubstituted s-triazines
    Paresh K. Patel
    Rahul V. Patel
    Dharmesh H. Mahajan
    Parimal A. Parikh
    Girish N. Mehta
    Kishor H. Chikhalia
    Medicinal Chemistry Research, 2012, 21 : 3182 - 3194
  • [26] Synthesis and Biological Evaluation of 1,2,3-Triazole-linked 18F-Labled PET Tracers for Imaging of PSMA
    Lee, B.
    Chu, S.
    Jung, H.
    Yang, S.
    Jung, W.
    Moon, H.
    Kim, M.
    Kim, J.
    Kil, H.
    Lee, Y.
    Lee, K.
    Woo, S.
    Kim, M.
    Lim, S.
    Lim, I.
    Chi, D.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2018, 45 : S40 - S40
  • [27] Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands
    Keck, Thomas M.
    Banala, Ashwini K.
    Slack, Rachel D.
    Burzynski, Caitlin
    Bonifazi, Alessandro
    Okunola-Bakare, Oluyomi M.
    Moore, Martin
    Deschamps, Jeffrey R.
    Rais, Rana
    Slusher, Barbara S.
    Newman, Amy Hauck
    BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 23 (14) : 4000 - 4012
  • [28] Design, Modeling and Synthesis of 1,2,3-Triazole-Linked Nucleoside-Amino Acid Conjugates as Potential Antibacterial Agents
    Malkowski, Sarah N.
    Dishuck, Carolyn F.
    Lamanilao, Gene G.
    Embry, Carter P.
    Grubb, Christopher S.
    Cafiero, Mauricio
    Peterson, Larryn W.
    MOLECULES, 2017, 22 (10):
  • [29] CuAAC-ensembled 1,2,3-triazole-linked isosteres as pharmacophores in drug discovery: review
    Rani, Alisha
    Singh, Gurjaspreet
    Singh, Akshpreet
    Maqbool, Ubair
    Kaur, Gurpreet
    Singh, Jandeep
    RSC ADVANCES, 2020, 10 (10) : 5610 - 5635
  • [30] Design, synthesis, characterization, and in vitro antimicrobial action of novel trisubstituted s-triazines
    Patel, Paresh K.
    Patel, Rahul V.
    Mahajan, Dharmesh H.
    Parikh, Parimal A.
    Mehta, Girish N.
    Chikhalia, Kishor H.
    MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (10) : 3182 - 3194