Principle for performing attractor transits with single control in Boolean networks

被引：23

作者：

Gao, Bo ^{[1
,2
,3
]}

Li, Lixiang ^{[2
]}

Peng, Haipeng ^{[2
]}

Kurths, Juergen ^{[4
]}

Zhang, Wenguang ^{[5
]}

Yang, Yixian ^{[1
,2
]}

机构：

[1] Beijing Jiaotong Univ, Sch Comp & Informat Technol, Beijing 100044, Peoples R China

[2] Beijing Univ Posts & Telecommun, State Key Lab Networking & Switching Technol, Informat Secur Ctr, Beijing 100876, Peoples R China

[3] Inner Mongolia Univ Finance & Econ, Sch Comp Informat Management, Hohhot 010051, Peoples R China

[4] Potsdam Inst Climate Impact Res, D-14473 Potsdam, Germany

[5] Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot 010018, Peoples R China

来源：

PHYSICAL REVIEW E | 2013年 / 88卷 / 06期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

Algebraic approaches - Boolean Networks - Control sequences - Dictyostelium discoideum - Gene Regulation Network - Protein-nucleic acid interaction - Semi-tensor product - State transition Matrix;

D O I：

10.1103/PhysRevE.88.062706

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We present an algebraic approach to reveal attractor transitions in Boolean networks under single control based on the recently developed matrix semitensor product theory. In this setting, the reachability of attractors is estimated by the state transition matrices. We then propose procedures that compute the shortest control sequence and the result of each step of input (control) exactly. The general derivation is exemplified by numerical simulations for two kinds of gene regulation networks, the protein-nucleic acid interactions network and the cAMP receptor of Dictyostelium discoideum network.

引用

页数：6

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